Browse Items · Pediatric Palliative Care Library

Breathing abnormalities in sleep in achondroplasia

Overnight sleep studies were performed in 20 subjects with achondroplasia to document further the respiratory abnormalities present in this group. Somatosensory evoked potentials (SEPs) were recorded in 19 of the subjects to screen for the presence…

Tags: 1993, achondroplasia, Archives in Disease in Childhood, breathing difficulties, characteristics, Everett F, Fagan E, Sillence D, Sullivan C E, Trajectory, upper airways obstruction, Waters K A

Occurrence of the Sandifer complex in the Brachmann-de Lange syndrome

Gastroesophageal reflux is a common occurrence in infancy. The most severe complications of reflux include torticollis, opisthotonus, and paroxysmal dystonic posture (known as the Sandifer complex). We examined 17 patients now ranging in age from 9…

TEACHING SELF-FEEDING SKILLS TO PATIENTS WITH RETT-SYNDROME

Few studies have examined the extent to which functional hand-use may be taught to girls with Rett syndrome after those skills have been lost. In this investigation, five females with classic Rett syndrome taught to feed themselves using a method of…

Tags: 1993, Anderson C, Developmental Medicine and Child Neurology, feeding difficulties, Fisher W, girls, Neurosciences & Neurology, Pediatrics, Piazza C C, psychological intervention, Rett syndrome, splints, tone and motor problems

Melatonin, cortisol and body temperature rhythms in Lennox-Gastaut patients with or without circadian rhythm sleep disorders

The daily rhythms of melatonin, cortisol and body temperature were studied in 16 institutionalized subjects with the Lennox-Gastaut syndrome. The results of 9 subjects with normal daily rhythms of sleep and wakefulness (group 1) were compared with…

Tags: 1993, Alila A, characteristics, congenital hydrocephalus, Hätönen T, Heiskala H, Journal Of Neurology, Laakso M L, Leinonen L, Lennox-Gastaut syndrome, LGS, sleep disturbance/disorders, Trajectory, West syndrome

Prospective study of spinal muscular atrophy before age 6 years. DCN/SMA Group

Spinal muscular atrophy (SMA) is a common neuromuscular disorder of childhood, associated with a high mortality rate during the first 2 years of life. Most practitioners expect patients with SMA to follow a progressive course with loss of muscle…

Development, behaviour and seizures in 300 cases of tuberous sclerosis

Three hundred cases of tuberous sclerosis were surveyed by postal questionnaire, including 240 cases with learning difficulties. People who have tuberous sclerosis and severe learning disabilities also have a higher frequency of epileptic seizures…

Assessing the clinical importance of symptomatic improvements. An illustration in rheumatology

OBJECTIVE: To estimate when a difference in disability symptoms is sufficiently large to be important to individual patients. DESIGN: Cross-sectional analysis of two groups: derivation set (n = 46) and validation set (n = 57). SETTING: The Arthritis…

Advice seeking and appropriate use of a pediatric emergency department

OBJECTIVES: To determine whether seeking advice prior to an unscheduled visit to a pediatric emergency department (PED) influences appropriate use of this setting for minor illnesses. DESIGN: Cross-sectional questionnaire survey. SETTING: The medical…

Confidentiality in health care. A survey of knowledge, perceptions, and attitudes among high school students

OBJECTIVE--To assess adolescent knowledge, perceptions, and attitudes about health care confidentiality. DESIGN--Anonymous self-report survey with 64 items addressing confidentiality issues in health care. SETTING--Rural, suburban, and urban high…

Clinical efficacy of methadone in patients refractory to other mu-opioid receptor agonist analgesics for management of terminal cancer pain. Case presentations and discussion of incomplete cross-tolerance among opioid agonist analgesics

BACKGROUND. Development of tolerance to opioid analgesics occurs often in patients with cancer-related pain. Cross-tolerance among opioid analgesics provides the physician with a major management problem. Incomplete cross-tolerance among opioid…

Occurrence of the Sandifer complex in the Brachmann-de Lange syndrome

Gastroesophageal reflux is a common occurrence in infancy. The most severe complications of reflux include torticollis, opisthotonus, and paroxysmal dystonic posture (known as the Sandifer complex). We examined 17 patients now ranging in age from 9…

Tags: 1993, Adolescent, Adult, American Journal Of Medical Genetics, Backlog, Child, De Lange Syndrome/complications, Esophagitis/complications/prevention & control, Gastroesophageal Reflux/complications, Humans, Infant, Journal Article, Posture, Sommer A, Spasm/complications, Torticollis/complications

Mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes (MELAS): clinical, radiological, pathological, and genetic observations

We reviewed 10 patients (5 males, 5 females) with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes. The age of symptom onset ranged from 3 months to 12 years. All had lactic acidosis, multiple stroke-like events with…

Work, knowledge and argument in specialist consultations: incorporating tacit knowledge into system design and development

To understand how video telephone technology could support consultations between pathologists and surgeons, this study looked at what constitutes 'work' in clinical consultations. Using several methods (participant observation, video and interviews),…

Tags: 1993, Backlog, Clinical, Communication, Hospital, Humans, Interprofessional Relations, Journal Article, Medical & Biological Engineering & Computing, Medical Staff, Non-U.S. Gov't, Nyce JM, Pathology, Research Support, Surgery, Timpka T

The Delphi technique: a comparison of results obtained using two expert panels

The Delphi technique is a useful method of obtaining group consensus. However, "consensus" is not usually defined when this technique is used. This paper describes a study in which two panels of experts (registered nurses who were nurse managers or…

Tags: 1993, Attitudes, Backlog, Delphi Technique, Duffield C, Health Knowledge, Humans, International Journal Of Nursing Studies, Job Description, Journal Article, New South Wales, Nursing, Nursing Administration Research, Practice, Professional Competence/standards, Supervisory/standards

Local analgesic effect of endogenous opioid peptides

Opioids produce analgesia by interacting with local opioid receptors in peripheral inflamed tissue. This study investigated whether endogenous ligands of these receptors are present in synovia and whether such opioid peptides can inhibit pain by…

Physician uncertainty and the art of persuasion

Incomplete information is a chronic feature of medica markets. Much attention has focused on information asymmetries between physicians and their patients. In contrast, physician uncertainty has received far less attention. This is a significant…

Tags: 1993, Backlog, Clinical Competence, Decision Making, Decision Support Techniques, Humans, Journal Article, Persuasive Communication, Physicians/psychology, Rizzo JA, Social science & medicine

Pituitary-adrenal function and hypothalamic beta-endorphin release in vitro following food deprivation

Basal and dexamethasone-suppressed adrenal glucocorticoid secretion and hypothalamic beta-endorphin (BE) release in vitro were investigated in rats deprived of food for 24, 48, 72, and 96 h. Fasting for up to 48 h neither caused significant changes…

Physiology of beta-endorphins. A close-up view and a review of the literature

When an endogenous morphine, beta-endorphin was discovered ten years ago, the fact that this morphine is present in the brain and many other tissues suggested to neurobiologists that these peptide opiates play a role which goes beyond that of a…

Tags: 1993, Backlog, Behavior/physiology, Bergal S, beta-Endorphin/physiology, Biomarkers of Pain, Biomarkers Reference List, Biomedicine & Pharmacotherapy, Dalayeun JF, Humans, Ion Channels/physiology, Journal Article, Neurotransmitter Agents, Nores JM, Pain/physiopathology

Brain and gut neuropeptides in peripheral blood mononuclear cells

Neuropeptides, initially thought to be common features of gut and brain, are only synthesized in immune cells and modulate immune functions. The presence and possible functions of these peptides in immune cells in both physiological or pathological…

Frequent school-based clinic utilization: a comparative profile of problems and service needs

The purpose of this study is to compare frequent users of school-based clinic services with students who have an average rate of utilization. SAMPLE: Of the 1413 students enrolled in a Denver school-based clinic (DSBC) during the 1989-1990 school…

Niemann-Pick disease type C: diagnosis and outcome in children, with particular reference to liver disease

The records of 52 children with Niemann-Pick disease type C were reviewed to establish whether the disease process and outcome varied with the initial clinical pattern; 34 children (65%) had cholestatic liver disease and hepatosplenomegaly in…

Recurrent metabolic decompensation in profound carnitine palmitoyltransferase II deficiency

A 3-year-old boy had recurrent episodes of lethargy, encephalopathy, and hepatomegaly accompanied by hypoglycemia, elevated liver aminotransferase and creatine kinase values, and nonketotic dicarboxylic aciduria; the serum carnitine level was…

Toxicity of local anesthetics in infants and children

Local anesthetics are extremely useful for providing anesthesia and analgesia for infants and children of all ages. Despite the toxicity issues raised here, the overall safety record of local anesthetic use in pediatrics has been very good, and local…

Tags: 1993, Absorption, Anesthetics, Backlog, Berde CB, Child, Humans, Infant, Journal Article, Local/administration & dosage/adverse effects/blood/pharmacokinetics/pharmacology, Risk Factors, The Journal Of Pediatrics

Update on epilepsy

1993

Tags: 1993, Backlog, Journal Article, Medical Clinics of North America, So EL

Bereavement care - the role of the paediatrician

1993

Tags: 1993, Backlog, Bereavement, Current Paediatrics, Journal Article, Role, Wilson R

Towards clarification of convergent concepts: sense of coherence, will to meaning, locus of control, learned helplessness and hardiness

The multidisciplinary field of stress and stress-related health outcomes has generated theoretical and practical knowledge which is of interest to nurses. Theoretical developments which have assumed a prominent role in the study of stress, health and…

Tags: 1993, Attitude, Backlog, Freedom, Health, Helplessness, Humans, Internal-External Control, Journal Article, Journal Of Advanced Nursing, Learned, Models, Nursing, Philosophy, Psychological, Psychological/psychology, Self Concept, Stress, Sullivan GC

Beta-endorphin levels are reduced in peripheral blood mononuclear cells of cluster headache patients

Opioid system hypofunction has been postulated in cluster headache (CH) on the basis of reduced opioid levels found in the cerebrospinal fluid (CSF). In this study beta-endorphin levels were monitored in the peripheral blood mononuclear cells of 65…

Tags: 1993, Adult, Backlog, beta-Endorphin/blood, Bussone G, Cephalalgia, Cluster Headache/blood, D'Amico D, Female, Humans, Journal Article, Leone M, Male, Monocytes/metabolism, Panerai AE, Reference Values, Sacerdote P

Disorders of movement in Leigh syndrome

Leigh syndrome (LS) is the clinical prototype of a genetically-determined mitochondrial encephalopathy. Twenty-two of 34 patients with LS had evidence of a movement disorder (MD). Dystonia, the most common MD, was present in 19 cases, rigidity in 4,…

Social and economic consequences of overweight in adolescence and young adulthood

BACKGROUND AND METHODS: Overweight in adolescents may have deleterious effects on their subsequent self-esteem, social and economic characteristics, and physical health. We studied the relation between overweight and subsequent educational…

Parental grief reactions and marital intimacy following infant death

1993

Tags: 1993, Backlog, Death, Death studies, Gottlieb LN, Grief, grief reaction, Infant, Infant Death, Journal Article, Lang A

Bereavement and mourning in pediatric rehabilitation settings

Developmental changes in children's acquisition of death concepts and in their emotional reactions are reviewed. Moderating variables that may affect the nature of grieving processes after parental or sibling death are discussed, including…

Tags: 1993, Attitude To Death, Backlog, Bereavement, Brain Injuries, Child, Death studies, Donders J, Hospitalized, Humans, Journal Article, Male, Parents, Preschool, Rehabilitation Centers, sibling bereavement, Sibling Relations, United States

Ventilatory effects of morphine, pethidine and methadone in children

The ventilatory effects of single i.v. doses of morphine 0.1 mg kg-1, pethidine 0.67 mg kg-1 and methadone 0.1 mg kg-1 were compared after ophthalmic surgery in an open, randomized study in 30 children aged 3-8 yr. Ventilatory changes after each drug…

Patient-controlled analgesia with low dose background infusions after lower abdominal surgery in children

Forty-five children (aged 6-12 yr) undergoing appendicectomy received one of three analgesic regimens using patient-controlled analgesia (PCA) with morphine: no background infusion (BO); background infusion 4 micrograms kg-1 h-1 (B4); background…

Pharmacokinetics of continuous infusions of fentanyl in critically ill children

OBJECTIVE: To determine the pharmacokinetics of fentanyl when used as a long-term continuous infusion for sedation/analgesia in mechanically ventilated critically ill infants and children. DESIGN: Prospective, case series. SETTING: A university…

Communication between physician, patient, and family in the pediatric intensive care unit

Rigor or rigor mortis: The problem of rigor in qualitative research revisited

1993

Tags: 1993, Advances in Nursing Science, Backlog, Journal Article, Qualitative Research, Research, Sandelowski M

Using high-dose morphine to relieve cancer pain

For cancer patients, the question of how much morphine is too much may be irrelevant-they need as much as it takes to relieve their pain. Discover the principles of administering high doses of morphine, including which routes to use, how to convert…

Tags: 1993, Adult, Backlog, Fulton JS, Humans, Infusions, Intravenous, Johnson GB, Journal Article, Male, Morphine/administration & dosage/adverse effects, Neoplasms/physiopathology, Nursing, Oncologic Nursing/methods, Pain/drug therapy/nursing

Nutrition-related growth failure of children with quadriplegic cerebral palsy

Growth failure and nutritional status were evaluated in 142 children with quadriplegic cerebral palsy, aged between two and 18 years. Linear growth was assessed by upper-arm and lower-leg lengths: both means were significantly reduced. Mean…

Reduced life expectancy in 40 cases of early onset cerebellar ataxia with retained tendon reflexes: a population-based study

A survival analysis of 40 cases of early onset cerebellar ataxia (EOCA) with retained tendon reflexes was performed. They represent all cases of EOCA diagnosed between 1945 and 1990 among residents of a defined area of Northwestern Italy, followed up…

Optimal pain relief in infants and children

1993

Tags: 1993, Analgesia/methods, Anesthesia/methods, Anesthetics/therapeutic use, Backlog, Berde CB, Bmj (clinical Research Ed.), Burrows FA, Humans, Infant, Journal Article, Morphine/therapeutic Use, Newborn, Pain Measurement, Pain/drug Therapy

Browse Items (61 total)