Browse Items (33 total)
- Tags: Double-Blind Method
Effect of melatonin dosage on sleep disorder in tuberous sclerosis complex
Tags: 2005, Administration Oral, Adult, Antioxidants/pharmacology/therapeutic use, Child, Child Preschool, Cross-Over Studies, Dose-Response Relationship Drug, Double-Blind Method, Female, Hancock E, Humans, Infant, Journal of Child Neurology, Male, melatonin, Melatonin/pharmacology/therapeutic use, O'Callaghan F, Osborne J P, pharmacologic intervention, sleep disturbance/disorders, Sleep Wake Disorders/drug therapy/etiology, Treatment Outcome, Tuberous Sclerosis, Tuberous Sclerosis/complications
Melatonin appears ineffective in children with intellectual deficits and fragmented sleep: six "N of 1" trials
Tags: 1996, Adolescent, Camfield C, Camfield P, Child, Child Preschool, Dooley J, Double-Blind Method, Female, Gordon K, Humans, Intellectual Disability/complications, Journal of Child Neurology, Male, melatonin, Melatonin/therapeutic use, neurodevelopmental disorder, pharmacologic intervention, sleep disturbance/disorders, Sleep Wake Disorders/drug therapy/etiology, undefined neurodevelopmental disorders
Melatonin treatment in individuals with intellectual disability and chronic insomnia: a randomized placebo-controlled study
Tags: 2008, Adolescent, Adult, Aged, Braam W, Central Nervous System Depressants/adverse effects/therapeutic use, Child, Child Preschool, chromosome 18q deletion, Chronic Disease, Comorbidity, Curfs L, Didden R, Double-Blind Method, Female, Humans, Journal Of Intellectual Disability Research, Male, melatonin, Melatonin/adverse effects/therapeutic use, Mental Retardation/epidemiology/psychology, Middle Aged, MPS III, pharmacologic intervention, Q3 Scoping Review Results, Saliva, sleep disturbance/disorders, Sleep Initiation and Maintenance Disorders/drug therapy/epidemiology/psychology, Smits M, Time Factors, Treatment Outcome
Sumatriptan-naproxen for acute treatment of migraine: a randomized trial
Tags: 2007, Adelman JU, Adult, Alexander WJ, Anti-Inflammatory Agents, Backlog, Barrett PS, Brandes JL, Double-Blind Method, Drug Combinations, Female, Humans, JAMA, Journal Article, Kudrow D, Lener SE, Male, Middle Aged, Migraine Disorders/drug therapy, Naproxen/administration & dosage/therapeutic use, Non-Steroidal/administration & dosage/therapeutic use, O'Carroll CP, O'Donnell FJ, Spruill SE, Stark SR, Sumatriptan/administration & dosage/therapeutic use, Tablets, Vasoconstrictor Agents/administration & dosage/therapeutic use
Effect of palliative oxygen versus room air in relief of breathlessness in patients with refractory dyspnoea: a double-blind, randomised controlled trial
Tags: 2010, Abernethy AP, Adult, Aged, Air, Anxiety/chemically induced, Australia, Backlog, Booth S, Bull J, Clark K, Crockett AJ, Currow DC, Double-Blind Method, Dyspnea/drug therapy/therapy, Epistaxis/chemically induced, Female, Frith PA, Great Britain, Herndon JE, Humans, Journal Article, Lancet, Male, Marcello J, McDonald CF, Middle Aged, Oxygen/administration & dosage/adverse effects/blood, Palliative Care/methods, Quality Of Life, Sleep, Sleep Stages, Treatment Outcome, Tulsky JA, United States, Wheeler JL, Wilcock A, Young IH
Miglustat for treatment of Niemann-Pick C disease: a randomised controlled study
Tags: 1-Deoxynojirimycin/analogs & derivatives/therapeutic use, 2007, Abel L, Adolescent, Adult, Age Factors, Analysis of Variance, Backlog, Child, Cohort Studies, Deglutition/drug effects, Double-Blind Method, Drug Administration Schedule, Enzyme Inhibitors/therapeutic use, Female, Humans, Journal Article, Lancet Neurology, Male, Niemann-Pick Disease, Patterson MC, Prady H, Preschool, Q3 Scoping Review Results, Retrospective Studies, Saccades/drug effects, Severity Of Illness Index, Type C/drug therapy/physiopathology, Vecchio D, Wraith JE
A D2 antagonist enhances the rewarding and priming effects of a gambling episode in pathological gamblers.
Tags: 2007, Adult, Analysis of Variance, Backlog, Blood Pressure/de [Drug Effects], Dopamine Antagonists/ad [Administration & Dosage], Dopamine Antagonists/ae [Adverse Effects], Double-Blind Method, Female, Gambling/px [Psychology], Haloperidol/ad [Administration & Dosage], Haloperidol/ae [Adverse Effects], Humans, IM, Journal Article, Male, Middle Aged, Motivation, Neuropsychological Tests, Neuropsychopharmacology, Pain Measurement, Poulos CX, Psychiatric Status Rating Scales, Reaction Time/de [Drug Effects], Reward, Semantics, Zack M
Melatonin treatment in individuals with intellectual disability and chronic insomnia: a randomized placebo-controlled study
Tags: 2008, Adolescent, Adult, Aged, Backlog, Braam W, Central Nervous System Depressants/adverse effects/therapeutic use, Child, Chronic Disease, Comorbidity, Curfs L, Didden R, Double-Blind Method, Female, Humans, Journal Article, Journal Of Intellectual Disability Research, Male, Melatonin/adverse effects/therapeutic use, Mental Retardation/epidemiology/psychology, Middle Aged, Preschool, Q3 Scoping Review Results, Saliva, Sleep Initiation and Maintenance Disorders/drug therapy/epidemiology/psychology, Smits M, Time Factors, Treatment Outcome
Smoked cannabis for chronic neuropathic pain: a randomized controlled trial
Tags: 2010, Adult, Aged, Backlog, Bennett GJ, Canadian Medical Association Journal, Chronic Disease, Collet JP, Cross-Over Studies, Double-Blind Method, Ducruet T, Female, Gamsa A, Humans, Huynh T, Journal Article, Linear Models, Male, Marijuana Smoking, Middle Aged, Neuralgia/drug therapy, Pain Measurement, Placebos, Quality Of Life, Robinson A, Shapiro S, Sleep/drug effects, Tetrahydrocannabinol/administration & dosage/adverse effects/therapeutic use, Treatment Outcome, Wang T, Ware M
Benefits of an add-on treatment with the synthetic cannabinomimetic nabilone on patients with chronic pain--a randomized controlled trial
Tags: 2006, Adjuvant, Anti-Anxiety Agents, Backlog, Cannabinoids/administration & dosage, Chemotherapy, Chronic Disease, Cross-Over Studies, Double-Blind Method, Female, Hiermann E, Humans, Journal Article, Male, Middle Aged, Pain Measurement/drug effects, Pain/drug Therapy, Pinsger M, Placebo Effect, Polz W, Quality Of Life, Riederer F, Schimetta W, Tetrahydrocannabinol/administration & dosage/analogs & derivatives, Treatment Outcome, Volc D, Wiener Klinische Wochenschrift
Effect of sublingual application of cannabinoids on intraocular pressure: a pilot study
Tags: 2006, Administration, Azuara-Blanco A, Backlog, Cannabidiol/administration & dosage, Cross-Over Studies, Double-Blind Method, Flint M, Glaucoma, House H, Humans, Intraocular Pressure/drug effects, Journal Article, Journal Of Glaucoma, Male, Middle Aged, Ocular Hypertension/drug therapy, Open-Angle/drug therapy, Pertwee RG, Pilot Projects, Psychotropic Drugs/administration & dosage, Robson PJ, Sublingual, Tetrahydrocannabinol/administration & dosage, Tomida I, Visual Acuity/drug effects
A double-blind, randomized, placebo-controlled trial of escitalopram in the treatment of pediatric depression
Tags: 2006, Adolescent, Backlog, Child, Citalopram/therapeutic use, Depressive Disorder, Diagnostic and Statistical Manual of Mental Disorders, Double-Blind Method, Extramural, Female, Findling RL, Humans, Jonas J, Journal Article, Journal Of The American Academy Of Child And Adolescent Psychiatry, Major/diagnosis/drug therapy, Male, N.I.H., Non-U.S. Gov't, PedPal Lit, Research Support, Saikali K, Serotonin Uptake Inhibitors/therapeutic use, Ventura D, Wagner KD
A prospective evaluation of opioid weaning in opioid-dependent pediatric critical care patients
Tags: 2006, Analgesics, Anesthesia & Analgesia, Backlog, Berens RJ, Child, Colpaert KD, Comparative Study, Critical Care/methods/statistics & numerical data, Czarnecki ML, Double-Blind Method, Female, Ghanayem NS, Hoffman GM, Humans, Infant, Journal Article, Male, Meyer MT, Mikhailov TA, Nelson TJ, Non-U.S. Gov't, Opioid-Related Disorders/epidemiology, Opioid/therapeutic use, Pain/drug therapy/epidemiology, PedPal Lit, Preschool, Prospective Studies, Research Support, Soetenga DJ, Substance Withdrawal Syndrome/epidemiology, Weisman SJ
Analgesic effect of the synthetic cannabinoid CT-3 on chronic neuropathic pain: a randomized controlled trial
Tags: 2003, Adult, Analgesics, Backlog, Burstein S, Chronic Disease, Conrad I, Cross-Over Studies, Double-Blind Method, Female, Hoy L, Humans, Hyperalgesia/complications/drug therapy, JAMA, Journal Article, Karst M, Male, Middle Aged, Non-Narcotic/therapeutic use, Non-U.S. Gov't, Pain Measurement, Pain/complications/drug therapy, Research Support, Salim K, Schneider U, Tetrahydrocannabinol/analogs & derivatives/therapeutic use
Opioids in chronic non-cancer pain: systematic review of efficacy and safety
Tags: 2004, Analgesics, Backlog, Chronic Disease, Comparative Study, Double-Blind Method, Drug Evaluation, Drug Utilization Review, Edwards JE, Humans, Journal Article, Kalso E, McQuay HJ, Methadone, Moore RA, Non-U.S. Gov't, Opioid/adverse effects/therapeutic use, Pain, Pain Measurement, Pain/drug Therapy, Randomized Controlled Trials/methods, Research Support, Time Factors, Treatment Outcome
Risperidone in children with autism and serious behavioral problems
Tags: 2002, Adolescent, Aman MG, Antipsychotic Agents/administration & dosage/adverse effects/therapeutic use, Arnold LE, Autistic Disorder/drug therapy/psychology, Backlog, Carroll D, Child, Child Behavior/drug effects, Comparative Study, Cronin P, Davies M, Double-Blind Method, Female, Ghuman J, Gonzalez NM, Grados M, Hollway J, Hong D, Humans, Journal Article, Koenig K, Kohn A, Lancor A, Lindsay R, Male, Martin A, McCracken JT, McDougle CJ, McGough J, McMahon D, Nash P, Non-U.S. Gov't, P.H.S., Posey D, Preschool, Research Support, Research Units on Pediatric Psychopharmacology (RUPP) Autism Network, Risperidone/administration & dosage/adverse effects/therapeutic use, Ritz L, Robinson J, Scahill L, Shah B, Swiezy N, The New England Journal Of Medicine, Tierney E, Treatment Outcome, U.S. Gov't, Vitiello B, Volkmar F
Increased numbers of opioid expressing inflammatory cells do not affect intra-articular morphine analgesia
Tags: 2004, Adult, Aged, Analgesics, Arthroscopy, Backlog, Biomarkers of Pain, British Journal Of Anaesthesia, Combination, Dose-Response Relationship, Double-Blind Method, Drug, Drug Therapy, Female, Humans, Injections, Intra-Articular, Journal Article, Knee Joint/metabolism/surgery, Koppert W, Likar R, Male, Middle Aged, Morphine/administration & dosage, Mousa SA, Opioid/administration & dosage, Opioid/metabolism, Pain Measurement/methods, Philippitsch G, Pirinitramide/administration & dosage, Receptors, Schafer M, Stein C, Steinkellner H, Synovitis/metabolism/pathology
Initial experiences with medicinal extracts of cannabis for chronic pain: results from 34 'N of 1' studies
Tags: 2004, Administration, Adult, Aged, Anaesthesia, Analgesics, Backlog, Cannabidiol/adverse effects/therapeutic use, Chronic Disease, Cross-Over Studies, Depressive Disorder/drug therapy, Double-Blind Method, Drug Combinations, Female, Humans, Journal Article, Male, Middle Aged, Miller R, Multiple Sclerosis/drug therapy, Newport S, Non-Narcotic/adverse effects/therapeutic use, Notcutt W, Pain Measurement/methods, Pain/drug Therapy, Patient Selection, Phillips C, Price M, Sansom C, Simmons S, Sleep/drug effects, Sublingual, Tetrahydrocannabinol/adverse effects/therapeutic use, Treatment Outcome
Activation of peripheral NMDA receptors contributes to human pain and rat afferent discharges evoked by injection of glutamate into the masseter muscle
Tags: 2003, Adult, Afferent Pathways/drug effects/physiology, Analysis of Variance, Animals, Arendt-Nielsen L, Backlog, Berde CB, Cairns BE, Cross-Over Studies, Dose-Response Relationship, Double-Blind Method, Drug, Female, Glutamic Acid/pharmacology, Graven-Nielsen T, Humans, Hupfeld S, Journal Article, Journal Of Neurophysiology, Male, Masseter Muscle/drug effects/physiology, N-Methyl-D-Aspartate/agonists/antagonists & inhibitors/metabolism, Non-U.S. Gov't, Nonparametric, Pain/chemically induced/physiopathology, Rats, Receptors, Research Support, Sessle BJ, Sprague-Dawley, Statistics, Svensson P, Wang K
Practice parameter: pharmacological treatment of migraine headache in children and adolescents: report of the American Academy of Neurology Quality Standards Subcommittee and the Practice Committee of the Child Neurology Society
Tags: 2004, Adolescent, American Academy of Neurology Quality Standards Subcommittee, Analgesics/classification/therapeutic use, Anti-Inflammatory Agents, Anticonvulsants/therapeutic use, Antidepressive Agents/therapeutic use, Antihypertensive Agents/therapeutic use, Ashwal S, Backlog, Calcium Channel Blockers/therapeutic use, Child, Cross-Over Studies, Double-Blind Method, Evidence-based Medicine, Female, Forecasting, Hershey A, Hirtz D, Humans, Journal Article, Lewis D, Male, Migraine Disorders/drug therapy/prevention & control, Neurology, Non-Steroidal/therapeutic use, Practice Committee of the Child Neurology Society, Preschool, Randomized Controlled Trials, Retrospective Studies, Serotonin Agonists/therapeutic use, Silberstein S, Yonker M
Risperidone in the treatment of disruptive behavioral symptoms in children with autistic and other pervasive developmental disorders
Tags: 2004, Aggression/drug effects, Antipsychotic Agents/adverse effects/pharmacology/therapeutic use, Autistic Disorder/drug therapy, Backlog, Carroll A, Child, Child Development Disorders, Dopamine Antagonists/therapeutic use, Double-Blind Method, Dunbar F, Female, Humans, Irritable Mood/drug effects, Journal Article, Male, Orlik H, Pediatrics, Pervasive/drug therapy, Preschool, Risperidone/adverse effects/pharmacology/therapeutic use, Schulz M, Serotonin Antagonists/therapeutic use, Shea S, Smith I, Treatment Outcome, Turgay A
Pharmacogenetics of codeine metabolism in an urban population of children and its implications for analgesic reliability
Tags: 2002, Analgesia, Analgesics, Anti-Inflammatory Agents, Backlog, British Journal Of Anaesthesia, Central Nervous System Stimulants/blood, Child, Codeine/genetics/metabolism, Diclofenac/administration & dosage, Double-Blind Method, Female, Genotype, Howard RF, Human, Journal Article, Male, Morphine Derivatives/blood, Morphine/metabolism, Non-Steroidal/administration & dosage, Non-U.S. Gov't, Opioid/metabolism, Patel A, Phenotype, Preschool, Support, Tonsillectomy, Urban Population, Vomiting/chemically induced, Williams DG
Oral opioid therapy for chronic peripheral and central neuropathic pain
Tags: 2003, 80 And Over, Adult, Aged, Analgesics, Backlog, Central Nervous System Diseases/drug therapy, Chronic Disease, Davies PS, Dose-Response Relationship, Double-Blind Method, Drug, Drug Tolerance, Female, Human, Journal Article, Levorphanol/administration & dosage/adverse effects/therapeutic use, Male, Middle Age, Mohr D, Neuralgia/drug therapy, New England Journal Of Medicine, Non-U.S. Gov't, Opioid/administration & dosage/adverse effects/therapeutic, Outcome Assessment (health Care), P.H.S., Peripheral Nervous System Diseases/drug therapy, Reisner L, Rowbotham MC, Support, Taylor K, Twilling L, U.S. Gov't, use
The n-of-1 randomized controlled trial: clinical usefulness. Our three-year experience
Tags: 1990, Adachi JD, Adult, Amitriptyline/therapeutic use, Annals Of Internal Medicine, Backlog, Clodronate, Double-Blind Method, Female, Guyatt GH, Humans, Jaeschke R, Journal Article, Keller JL, Newhouse MT, Patient Compliance, Physician's Role, Propranolol/therapeutic use, Randomized Controlled Trials/methods, Research Design, Rosenbloom D, Syncope/drug therapy
Comparative clinical efficacy and safety of a novel controlled-release oxycodone formulation and controlled-release hydromorphone in the treatment of cancer pain
Tags: 1997, Analgesics, Babul N, Backlog, Cancer, Comparative Study, Cross-Over Studies, Delayed-Action Preparations, Double-Blind Method, Drug Evaluation, Female, Hagen NA, Humans, Hydromorphone/administration & Male, Journal Article, Middle Aged, Neoplasms/complications, Opioid/administration & dosage, Oxycodone/administration & Pain/drug therapy
Comparative clinical efficacy and safety of immediate release and controlled release hydromorphone for chronic severe cancer pain
Tags: 1994, Babul N, Backlog, Cancer, Chronic Disease, Darke AC, Delayed-Action Preparations, Dhaliwal H, Double-Blind Method, Drug Administration Schedule, Female, Hagen N, Harsanyi Z, Hays H, Humans, Hydromorphone/administration & dosage, Journal Article, Male, Middle Aged, Neoplasms/complications, Pain Measurement, Pain/drug therapy/etiology, Thirlwell M
Comparison of continuous subcutaneous and intravenous hydromorphone infusions for management of cancer pain
Tags: 1991, Aged, Backlog, Bouquillon AI, Comparative Study, Double-Blind Method, Evaluation Studies, Female, Humans, Hydromorphone/administration & dosage/adverse effects/blood/therapeutic use, Implantable, Infusion Pumps, Infusions, Intravenous, Journal Article, Kreeft JH, Lancet, Male, Middle Aged, Moulin DE, Murray-Parsons N, Neoplasms/blood/physiopathology, Non-U.S. Gov't, Pain/blood/drug therapy/etiology, Palliative Care/methods, Parenteral/methods, Research Support, Severity Of Illness Index, Time Factors
Local analgesic effect of endogenous opioid peptides
Tags: 1993, Adult, Aged, Arthroscopy, Backlog, beta-Endorphin/analysis/physiology, Biomarkers of Pain, Double-Blind Method, Dynorphins/analysis/physiology, Endorphins/analysis/physiology, Enkephalin, Giefing J, Hassan AH, Humans, Immunohistochemistry, Injections, Intra-Articular, Intravenous, Journal Article, Knee Joint/surgery, Lancet, Lehrberger K, Methionine/analysis/physiology, Middle Aged, Naloxone/administration & dosage/pharmacology, Opioid/drug effects, Pain, Postoperative/etiology, Receptors, Stein C, Synovial Membrane/chemistry, Synovitis/metabolism, Yassouridis A
A double-blind, crossover trial of intravenous clodronate in metastatic bone pain
Tags: 1992, 80 And Over, Adult, Aged, Backlog, Bone Neoplasms/physiopathology/secondary, Brasher P, Bruera E, Clodronate, Clodronic Acid/administration & dosage/therapeutic use, Double-Blind Method, Ernst DS, Female, Humans, Infusions, Intravenous, Jensen J, Journal Article, Journal of Pain and Symptom Management, MacDonald RN, Male, Middle Aged, Pain Measurement, Pain/diagnosis/drug therapy/etiology, Paterson AH
Patient-controlled analgesia for mucositis pain in children: a three-period crossover study comparing morphine and hydromorphone
Tags: 1996, Adolescent, Analgesia, Analgesics, Analysis of Variance, Backlog, Berde CB, Child, Collins J J, Comparative Study, Cross-Over Studies, Double-Blind Method, Geake J, Grier HE, Houck CS, Humans, Hydromorphone/adverse effects/pharmacokinetics/therapeutic use, Inflammation/complications, Journal Article, Morphine/adverse effects/pharmacokinetics/therapeutic use, Mucous Membrane, Non-U.S. Gov't, Opioid/adverse effects/pharmacokinetics/therapeutic use, Pain Measurement, Pain/drug therapy/etiology, Patient-Controlled, Research Support, Thaler HT, The Journal Of Pediatrics, Therapeutic Equivalency, Treatment Outcome, Twum-Danso NY, Weinstein HJ
Neostigmine for the treatment of acute colonic pseudo-obstruction
Tags: 1999, 80 And Over, Abdominal Pain/chemically induced, Acute Disease, Adult, Aged, Backlog, Cholinesterase Inhibitors/adverse effects/therapeutic use, Colonic Pseudo-Obstruction/drug therapy, Double-Blind Method, Female, Humans, Journal Article, Kimmey MB, Male, Middle Aged, Neostigmine/adverse effects/therapeutic use, Ponec RJ, Recurrence, Saunders MD, The New England Journal Of Medicine
Comparison of morphine and methadone for prevention of postoperative pain in 3- to 7-year-old children
Tags: 1991, algorithms, Analysis of Variance, Backlog, Berde CB, Beyer JE, Bournaki MC, Child, Comparative Study, Double-Blind Method, Drug Evaluation, Female, Human, Intraoperative Care, Journal Article, Journal of Pediatrics, Levin CR, Male, Methadone/adverse effects/pharmacokinetics/therapeutic use, Morphine/adverse effects/therapeutic use, Non-U.S. Gov't, Pain, Pain Measurement, Postoperative/prevention & control, Preschool, Prospective Studies, Sethna NF, Support
What do plasma beta-endorphin levels reveal about endogenous opioid analgesic function?
Tags: 2012, Acute Pain/blood/physiopathology, Adult, Analgesia/methods, Backlog, beta-Endorphin/blood, Biomarkers of Pain, Bruehl S, Burns JW, Chont M, Chronic Pain/blood/physiopathology, Chung OY, Cross-Over Studies, Double-Blind Method, European Journal Of Pain, Female, Humans, Journal Article, Low Back Pain/blood/physiopathology, Male, Middle Aged, Naloxone/pharmacology, Narcotic Antagonists/pharmacology, Pain Measurement/drug effects, Pain Threshold/drug effects/physiology, Physical Stimulation