Occurrence of the Sandifer complex in the Brachmann-de Lange syndrome

Title

Occurrence of the Sandifer complex in the Brachmann-de Lange syndrome

Creator

Sommer A

Publisher

American Journal of Medical Genetics

Date

1993

Subject

Child; Humans; Adult; Adolescent; Infant; Posture; De Lange Syndrome/complications; Esophagitis/complications/prevention & control; Gastroesophageal Reflux/complications; Spasm/complications; Torticollis/complications; NET Files; child; adult; De Lange Syndrome/co [Complications]; Gastroesophageal Reflux/co [Complications]; Torticollis/co [Complications]; Esophagitis/co [Complications]; Esophagitis/pc [Prevention & Control]; Spasm/co [Complications]; feeding difficulties; De Lange syndrome; trajectory; characteristics; gastroesophageal reflux; GERD; Sandifer complex

Description

Gastroesophageal reflux is a common occurrence in infancy. The most severe complications of reflux include torticollis, opisthotonus, and paroxysmal dystonic posture (known as the Sandifer complex). We examined 17 patients now ranging in age from 9 months to 19 years (mean age 11 years) with the Brachmann-de Lange syndrome for evidence of gastroesophageal reflux and found that 13 had not only reflux, but also posturing and behavior consistent with the Sandifer complex. We propose that early recognition of gastroesophageal reflux in these patients may prevent the full picture of the Sandifer complex and allow for medical treatment rather than surgical intervention.

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Citation

Sommer A, “Occurrence of the Sandifer complex in the Brachmann-de Lange syndrome,” Pediatric Palliative Care Library, accessed September 24, 2021, https://pedpalascnetlibrary.omeka.net/items/show/16810.

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