Browse Items · Pediatric Palliative Care Library

Niemann-Pick disease type C: diagnosis and outcome in children, with particular reference to liver disease

The records of 52 children with Niemann-Pick disease type C were reviewed to establish whether the disease process and outcome varied with the initial clinical pattern; 34 children (65%) had cholestatic liver disease and hepatosplenomegaly in…

Frequent school-based clinic utilization: a comparative profile of problems and service needs

The purpose of this study is to compare frequent users of school-based clinic services with students who have an average rate of utilization. SAMPLE: Of the 1413 students enrolled in a Denver school-based clinic (DSBC) during the 1989-1990 school…

Brain and gut neuropeptides in peripheral blood mononuclear cells

Neuropeptides, initially thought to be common features of gut and brain, are only synthesized in immune cells and modulate immune functions. The presence and possible functions of these peptides in immune cells in both physiological or pathological…

Physiology of beta-endorphins. A close-up view and a review of the literature

When an endogenous morphine, beta-endorphin was discovered ten years ago, the fact that this morphine is present in the brain and many other tissues suggested to neurobiologists that these peptide opiates play a role which goes beyond that of a…

Tags: 1993, Backlog, Behavior/physiology, Bergal S, beta-Endorphin/physiology, Biomarkers of Pain, Biomarkers Reference List, Biomedicine & Pharmacotherapy, Dalayeun JF, Humans, Ion Channels/physiology, Journal Article, Neurotransmitter Agents, Nores JM, Pain/physiopathology

Pituitary-adrenal function and hypothalamic beta-endorphin release in vitro following food deprivation

Basal and dexamethasone-suppressed adrenal glucocorticoid secretion and hypothalamic beta-endorphin (BE) release in vitro were investigated in rats deprived of food for 24, 48, 72, and 96 h. Fasting for up to 48 h neither caused significant changes…

Physician uncertainty and the art of persuasion

Incomplete information is a chronic feature of medica markets. Much attention has focused on information asymmetries between physicians and their patients. In contrast, physician uncertainty has received far less attention. This is a significant…

Tags: 1993, Backlog, Clinical Competence, Decision Making, Decision Support Techniques, Humans, Journal Article, Persuasive Communication, Physicians/psychology, Rizzo JA, Social science & medicine

Local analgesic effect of endogenous opioid peptides

Opioids produce analgesia by interacting with local opioid receptors in peripheral inflamed tissue. This study investigated whether endogenous ligands of these receptors are present in synovia and whether such opioid peptides can inhibit pain by…

The Delphi technique: a comparison of results obtained using two expert panels

The Delphi technique is a useful method of obtaining group consensus. However, "consensus" is not usually defined when this technique is used. This paper describes a study in which two panels of experts (registered nurses who were nurse managers or…

Tags: 1993, Attitudes, Backlog, Delphi Technique, Duffield C, Health Knowledge, Humans, International Journal Of Nursing Studies, Job Description, Journal Article, New South Wales, Nursing, Nursing Administration Research, Practice, Professional Competence/standards, Supervisory/standards

Work, knowledge and argument in specialist consultations: incorporating tacit knowledge into system design and development

To understand how video telephone technology could support consultations between pathologists and surgeons, this study looked at what constitutes 'work' in clinical consultations. Using several methods (participant observation, video and interviews),…

Tags: 1993, Backlog, Clinical, Communication, Hospital, Humans, Interprofessional Relations, Journal Article, Medical & Biological Engineering & Computing, Medical Staff, Non-U.S. Gov't, Nyce JM, Pathology, Research Support, Surgery, Timpka T

Mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes (MELAS): clinical, radiological, pathological, and genetic observations

We reviewed 10 patients (5 males, 5 females) with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes. The age of symptom onset ranged from 3 months to 12 years. All had lactic acidosis, multiple stroke-like events with…

Occurrence of the Sandifer complex in the Brachmann-de Lange syndrome

Gastroesophageal reflux is a common occurrence in infancy. The most severe complications of reflux include torticollis, opisthotonus, and paroxysmal dystonic posture (known as the Sandifer complex). We examined 17 patients now ranging in age from 9…

Tags: 1993, Adolescent, Adult, American Journal Of Medical Genetics, Backlog, Child, De Lange Syndrome/complications, Esophagitis/complications/prevention & control, Gastroesophageal Reflux/complications, Humans, Infant, Journal Article, Posture, Sommer A, Spasm/complications, Torticollis/complications

Clinical efficacy of methadone in patients refractory to other mu-opioid receptor agonist analgesics for management of terminal cancer pain. Case presentations and discussion of incomplete cross-tolerance among opioid agonist analgesics

BACKGROUND. Development of tolerance to opioid analgesics occurs often in patients with cancer-related pain. Cross-tolerance among opioid analgesics provides the physician with a major management problem. Incomplete cross-tolerance among opioid…

Confidentiality in health care. A survey of knowledge, perceptions, and attitudes among high school students

OBJECTIVE--To assess adolescent knowledge, perceptions, and attitudes about health care confidentiality. DESIGN--Anonymous self-report survey with 64 items addressing confidentiality issues in health care. SETTING--Rural, suburban, and urban high…

Advice seeking and appropriate use of a pediatric emergency department

OBJECTIVES: To determine whether seeking advice prior to an unscheduled visit to a pediatric emergency department (PED) influences appropriate use of this setting for minor illnesses. DESIGN: Cross-sectional questionnaire survey. SETTING: The medical…

Assessing the clinical importance of symptomatic improvements. An illustration in rheumatology

OBJECTIVE: To estimate when a difference in disability symptoms is sufficiently large to be important to individual patients. DESIGN: Cross-sectional analysis of two groups: derivation set (n = 46) and validation set (n = 57). SETTING: The Arthritis…

Development, behaviour and seizures in 300 cases of tuberous sclerosis

Three hundred cases of tuberous sclerosis were surveyed by postal questionnaire, including 240 cases with learning difficulties. People who have tuberous sclerosis and severe learning disabilities also have a higher frequency of epileptic seizures…

Prospective study of spinal muscular atrophy before age 6 years. DCN/SMA Group

Spinal muscular atrophy (SMA) is a common neuromuscular disorder of childhood, associated with a high mortality rate during the first 2 years of life. Most practitioners expect patients with SMA to follow a progressive course with loss of muscle…

Melatonin, cortisol and body temperature rhythms in Lennox-Gastaut patients with or without circadian rhythm sleep disorders

The daily rhythms of melatonin, cortisol and body temperature were studied in 16 institutionalized subjects with the Lennox-Gastaut syndrome. The results of 9 subjects with normal daily rhythms of sleep and wakefulness (group 1) were compared with…

Tags: 1993, Alila A, characteristics, congenital hydrocephalus, Hätönen T, Heiskala H, Journal Of Neurology, Laakso M L, Leinonen L, Lennox-Gastaut syndrome, LGS, sleep disturbance/disorders, Trajectory, West syndrome

Browse Items (61 total)

Niemann-Pick disease type C: diagnosis and outcome in children, with particular reference to liver disease

Frequent school-based clinic utilization: a comparative profile of problems and service needs

Brain and gut neuropeptides in peripheral blood mononuclear cells

Physiology of beta-endorphins. A close-up view and a review of the literature

Pituitary-adrenal function and hypothalamic beta-endorphin release in vitro following food deprivation

Physician uncertainty and the art of persuasion

Local analgesic effect of endogenous opioid peptides

The Delphi technique: a comparison of results obtained using two expert panels

Work, knowledge and argument in specialist consultations: incorporating tacit knowledge into system design and development

Mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes (MELAS): clinical, radiological, pathological, and genetic observations

Occurrence of the Sandifer complex in the Brachmann-de Lange syndrome

Clinical efficacy of methadone in patients refractory to other mu-opioid receptor agonist analgesics for management of terminal cancer pain. Case presentations and discussion of incomplete cross-tolerance among opioid agonist analgesics

Confidentiality in health care. A survey of knowledge, perceptions, and attitudes among high school students

Advice seeking and appropriate use of a pediatric emergency department

Assessing the clinical importance of symptomatic improvements. An illustration in rheumatology

Development, behaviour and seizures in 300 cases of tuberous sclerosis

Prospective study of spinal muscular atrophy before age 6 years. DCN/SMA Group

Melatonin, cortisol and body temperature rhythms in Lennox-Gastaut patients with or without circadian rhythm sleep disorders

TEACHING SELF-FEEDING SKILLS TO PATIENTS WITH RETT-SYNDROME

Occurrence of the Sandifer complex in the Brachmann-de Lange syndrome

Breathing abnormalities in sleep in achondroplasia