Disease severity in children and adults with Pompe disease related to age and disease duration

Title

Disease severity in children and adults with Pompe disease related to age and disease duration

Creator

Hagemans ML; Winkel LP; Hop WC; Reuser AJ; Van Doorn PA; Van der Ploeg AT

Publisher

Neurology

Date

2005

Subject

Child; Cross-Sectional Studies; Female; Humans; infant; Male; Adult; Questionnaires; Aged; Middle Aged; Disease Progression; Age Factors; Respiration; Severity of Illness Index; Activities of Daily Living; adolescent; Preschool; 80 and over; infant; Q3 Literature Search; Newborn; Age of Onset; Muscle; Artificial/statistics & numerical data; Glycogen Storage Disease Type II/diagnosis/epidemiology/physiopathology; Respiratory Insufficiency/epidemiology/etiology/therapy; Skeletal/physiopathology; Wheelchairs/statistics & numerical data

Description

Information about 255 children and adults with Pompe disease was gathered through a questionnaire. Disease severity was associated with disease duration and not with age; an early manifestation of the disease implied earlier wheelchair or ventilator dependency. The patient group under age 15 included a subgroup with a more severe and rapid course of the disease. They require more intensive follow-up and early intervention, before irreversible damage has occurred.
2005

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

2139-2141

Issue

12

Volume

64

Citation

Hagemans ML; Winkel LP; Hop WC; Reuser AJ; Van Doorn PA; Van der Ploeg AT, “Disease severity in children and adults with Pompe disease related to age and disease duration,” Pediatric Palliative Care Library, accessed December 4, 2021, https://pedpalascnetlibrary.omeka.net/items/show/13344.

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