Postoperative epidural analgesia with bupivacaine and fentanyl: hourly pain assessment in 348 paediatric cases

Postoperative epidural analgesia with bupivacaine and fentanyl: hourly pain assessment in 348 paediatric cases

Lejus C; Surbled M; Schwoerer D; Renaudin M; Guillaud C; Berard L; Pinaud M

Paediatric Anaesthesia

2001

Child; Female; Humans; infant; Male; Pain; Analgesics; Prospective Studies; Analgesia; Anesthetics; adolescent; Preschool; infant; Newborn; Pain Measurement/drug effects; Opioid/administration & dosage/adverse effects/therapeutic use; Sleep/drug effects; Postoperative/drug therapy; Bupivacaine/administration & dosage/adverse effects/therapeutic use; Epidural/adverse effects; Fentanyl/administration & dosage/adverse effects/therapeutic use; Local/administration & dosage/adverse effects/therapeutic use

BACKGROUND: The objective of this prospective study was the evaluation of the analgesia provided by an epidural infusion of bupivacaine and fentanyl after different types of surgery in children. METHODS: Data were collected from 348 epidural analgesia in 87 children below 2 years of age, in 80 children between 2 and 6 years and 181 above 6 years of age, for a median duration of 43 postoperative hours. Bupivacaine (mean concentration 0.185%) and fentanyl (5 microg.kg-1.day-1) were administered on the surgical ward. RESULTS: Pain control was considered excellent in 86% of the 11 072 pain hourly assessments. Analgesia was found to be better for children older than 2 years, and the overall quality of their night's sleep was better than that of older children. Higher pain scores were noted for Nissen fundoplication surgery and club foot repairs. Early discontinuation rarely occurred, and only because of technical problems with the epidural catheter (4%) or insufficient analgesia (6%). Complications were minor (nausea/vomiting 14%, pruritus 0.6%, urinary retention 17%) and easily reversed. CONCLUSIONS: This combination of bupivacaine-fentanyl provides safe analgesia after major surgery in children with frequent clinical monitoring. Regular pain assessments of intensity and duration are useful to improve the quality of postoperative analgesia.

2001

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