Duration and morbidity of newly diagnosed idiopathic thrombocytopenic purpura in children: A prospective Nordic study of an unselected cohort

Duration and morbidity of newly diagnosed idiopathic thrombocytopenic purpura in children: A prospective Nordic study of an unselected cohort

Rosthoj S; Hedlund-Treutiger I; Rajantie J; Zeller B; Jonsson OG; Elinder G; Wesenberg F; Henter JI; NOPHOITP Working Group

The Journal Of Pediatrics

2003

Child; Female; Humans; infant; Male; Cohort Studies; Prospective Studies; Severity of Illness Index; Risk Assessment; Time Factors; adolescent; Preschool; infant; Newborn; Platelet Count; Purpura; Thrombocytopenic; Hemorrhage/diagnosis/etiology/therapy; Idiopathic/complications/diagnosis/therapy; Scandinavia

OBJECTIVE: To determine the duration of the risk period with platelet counts 1 month and 25 had 30 events. Among 93 patients with chronic ITP, 73 were at risk >1 month and 44 had 111 events. Events occurred with an average frequency of 0.39 per month at risk. Life-threatening hemorrhages did not occur in the first six months after diagnosis. CONCLUSION: Most children with ITP are at risk for serious bleeding for less than one month. Continuing severe thrombocytopenia is associated with little morbidity, bleeding episodes being infrequent and very rarely serious.

2003

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