On the mathematical modelling of pain

Title

On the mathematical modelling of pain

Creator

Britton NF; Skevington SM

Identifier

Publisher

Neurochemical Research

Date

1996

Subject

Humans; Analgesia; Reproducibility of Results; Animals; Models; Pain/physiopathology; Axons/physiology; Nerve Net/physiology; Neurological; Neuronal Plasticity; Neurons/physiology; Theoretical

Description

In this review a case is presented for the use of mathematical modelling in the study of pain. The philosophy of mathematical modelling is outlined and a recommendation is made for the use of modern nonlinear techniques and computational neuroscience in the modelling of pain. Classic and more recent examples of modelling in neurobiology in general and pain in particular, at three different levels-molecular, cellular and neural networks-are described and evaluated. Directions for further progress are indicated, particularly in plasticity and in modelling brain mechanisms. Major advantages of mathematical modelling are that it can handle extremely complex theories and it is non-invasive, and so is particularly valuable in the investigation of chronic pain.
1996

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

1133-1140

Issue

9

Volume

21

Citation

Britton NF; Skevington SM, “On the mathematical modelling of pain,” Pediatric Palliative Care Library, accessed July 4, 2022, https://pedpalascnetlibrary.omeka.net/items/show/12313.

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