Attacking pain at its source: new perspectives on opioids

Title

Attacking pain at its source: new perspectives on opioids

Creator

Stein C; Schafer M; Machelska H

Identifier

Publisher

Nature Medicine

Date

2003

Subject

Humans; Analgesics; Animals; Non-U.S. Gov't; Research Support; Drug Tolerance; Receptors; Ligands; Afferent/metabolism; Cell Movement; Neurons; Opioid Peptides/metabolism/therapeutic use; Opioid/genetics/metabolism; Opioid/metabolism/therapeutic use; Pain/drug therapy/metabolism/therapy; Signal Transduction/physiology

Description

The treatment of severe pain with opioids has thus far been limited by their unwanted central side effects. Recent research promises new approaches, including opioid analgesics acting outside the central nervous system, targeting of opioid peptide-containing immune cells to peripheral damaged tissue, and gene transfer to enhance opioid production at sites of injury.
2003

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

1003-1008

Issue

8

Volume

9

Citation

Stein C; Schafer M; Machelska H, “Attacking pain at its source: new perspectives on opioids,” Pediatric Palliative Care Library, accessed October 24, 2021, https://pedpalascnetlibrary.omeka.net/items/show/12961.

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