T-lymphocyte cholecystokinin-8 and beta-endorphin concentrations in eating disorders: I. Anorexia nervosa

Title

T-lymphocyte cholecystokinin-8 and beta-endorphin concentrations in eating disorders: I. Anorexia nervosa

Creator

Brambilla F; Brunetta M; Peirone A; Perna G; Sacerdote P; Manfredi B; Panerai AE

Publisher

Psychiatry Research

Date

1995

Subject

Child; Female; Humans; Adult; Treatment Outcome; Combined Modality Therapy; adolescent; Comparative Study; beta-Endorphin/blood; Cognitive Therapy; Anorexia Nervosa/blood/therapy; Antidepressive Agents/administration & dosage; Dibenzocycloheptenes/administration & dosage; Fluoxetine/administration & dosage; Nortriptyline/administration & dosage; Sincalide/blood; T-Lymphocytes/drug effects/metabolism

Description

Baseline concentrations of cholecystokinin-8 (CCK-8) and beta-endorphin (beta-EP) were measured in T-lymphocytes from 33 restricting patients with anorexia nervosa (AN-R), 23 binging/purging patients with anorexia nervosa (AN-BP), and 24 healthy volunteers. CCK-8 basal values were significantly lower and beta-EP values significantly higher in AN-R and AN-BP patients than in normal volunteers. Levels of the peptides were measured three more times during a 4-month combined cognitive-behavioral/psychopharmacological treatment (nortriptyline or fluoxetine in AN-R, fluoxetine or amineptine in AN-BP). CCK-8 values fluctuated (nonsignificantly) during each treatment, while beta-EP values decreased (to a significant degree only in fluoxetine-treated AN-R patients).
1995

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

43-50

Issue

1

Volume

59

Citation

Brambilla F; Brunetta M; Peirone A; Perna G; Sacerdote P; Manfredi B; Panerai AE, “T-lymphocyte cholecystokinin-8 and beta-endorphin concentrations in eating disorders: I. Anorexia nervosa,” Pediatric Palliative Care Library, accessed October 15, 2021, https://pedpalascnetlibrary.omeka.net/items/show/12300.

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