T-lymphocyte cholecystokinin-8 and beta-endorphin concentrations in eating disorders: I. Anorexia nervosa
Title
T-lymphocyte cholecystokinin-8 and beta-endorphin concentrations in eating disorders: I. Anorexia nervosa
Creator
Brambilla F; Brunetta M; Peirone A; Perna G; Sacerdote P; Manfredi B; Panerai AE
Identifier
Publisher
Psychiatry Research
Date
1995
Subject
Child; Female; Humans; Adult; Treatment Outcome; Combined Modality Therapy; adolescent; Comparative Study; beta-Endorphin/blood; Cognitive Therapy; Anorexia Nervosa/blood/therapy; Antidepressive Agents/administration & dosage; Dibenzocycloheptenes/administration & dosage; Fluoxetine/administration & dosage; Nortriptyline/administration & dosage; Sincalide/blood; T-Lymphocytes/drug effects/metabolism
Description
Baseline concentrations of cholecystokinin-8 (CCK-8) and beta-endorphin (beta-EP) were measured in T-lymphocytes from 33 restricting patients with anorexia nervosa (AN-R), 23 binging/purging patients with anorexia nervosa (AN-BP), and 24 healthy volunteers. CCK-8 basal values were significantly lower and beta-EP values significantly higher in AN-R and AN-BP patients than in normal volunteers. Levels of the peptides were measured three more times during a 4-month combined cognitive-behavioral/psychopharmacological treatment (nortriptyline or fluoxetine in AN-R, fluoxetine or amineptine in AN-BP). CCK-8 values fluctuated (nonsignificantly) during each treatment, while beta-EP values decreased (to a significant degree only in fluoxetine-treated AN-R patients).
1995
Rights
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Type
Journal Article
Citation List Month
Backlog
URL Address
Citation
Brambilla F; Brunetta M; Peirone A; Perna G; Sacerdote P; Manfredi B; Panerai AE, “T-lymphocyte cholecystokinin-8 and beta-endorphin concentrations in eating disorders: I. Anorexia nervosa,” Pediatric Palliative Care Library, accessed February 11, 2025, https://pedpalascnetlibrary.omeka.net/items/show/12300.