T-lymphocyte concentrations of cholecystokinin-8 and beta-endorphin in eating disorders: II. Bulimia nervosa

Title

T-lymphocyte concentrations of cholecystokinin-8 and beta-endorphin in eating disorders: II. Bulimia nervosa

Creator

Brambilla F; Brunetta M; Draisci A; Peirone A; Perna G; Sacerdote P; Manfredi B; Panerai AE

Publisher

Psychiatry Research

Date

1995

Subject

Female; Humans; Adult; Middle Aged; Treatment Outcome; Antidepressive Agents; Combined Modality Therapy; adolescent; Comparative Study; beta-Endorphin/blood; Cognitive Therapy; Dibenzocycloheptenes/administration & dosage; Sincalide/blood; T-Lymphocytes/drug effects/metabolism; Bulimia/blood/therapy; Fluvoxamine/administration & dosage; Serotonin Uptake Inhibitors/administration & dosage; Tricyclic/administration & dosage

Description

Concentrations of cholecystokinin-8 (CCK-8) and beta-endorphin (beta-EP) in T-lymphocytes of 26 women with bulimia nervosa (BN) and in 26 age- and sex-matched healthy comparison subjects were measured. Ten patients were then treated with 300 mg/day of fluvoxamine, p.o., and five patients were treated with 300 mg/day of amineptine, p.o., for 4 months. Concentrations of the two peptides were measured again after 1, 2, and 4 months of therapy. Basal CCK-8 values were significantly lower in patients than in healthy subjects. During fluvoxamine therapy, CCK-8 values increased, reaching normal levels by month 4 of treatment. No such increase occurred during amineptine therapy. Baseline beta-EP values were normal in the bulimic patients but had declined by month 4 of fluvoxamine therapy.
1995

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

51-56

Issue

1

Volume

37

Citation

Brambilla F; Brunetta M; Draisci A; Peirone A; Perna G; Sacerdote P; Manfredi B; Panerai AE, “T-lymphocyte concentrations of cholecystokinin-8 and beta-endorphin in eating disorders: II. Bulimia nervosa,” Pediatric Palliative Care Library, accessed November 30, 2021, https://pedpalascnetlibrary.omeka.net/items/show/12299.

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