Comparison of different bolus doses of morphine for patient-controlled analgesia in children

Title

Comparison of different bolus doses of morphine for patient-controlled analgesia in children

Creator

Doyle E; Mottart KJ; Marshall C; Morton NS

Publisher

British Journal Of Anaesthesia

Date

1994

Subject

Child; Female; Male; Pain; Pain Measurement; Time Factors; Non-U.S. Gov't; Comparative Study; Nausea/chemically induced; Human; Support; Adolescence; Patient-Controlled; Sleep/drug effects; Vomiting/chemically induced; Appendectomy; Analgesia; Morphine/administration & dosage/adverse effects; Postoperative/prevention & control

Description

Forty children undergoing appendicectomy were allocated randomly to receive one of two PCA regimens with morphine. Group B10 received bolus doses of 10 micrograms kg-1 and group B20 received bolus doses of 20 micrograms kg-1. In both groups there was a lockout interval of 5 min and a background infusion of 4 micrograms kg-1 h-1. Group B20 self-administered considerably more morphine (P < 0.01) than group B10. There was no difference between the pain scores of the groups at rest. Group B20 had significantly (P < 0.05) smaller pain scores during movement than group B10 and the latter group suffered significantly (P < 0.01) more hypoxaemic episodes than group B20. There were no differences between the groups in the incidence of vomiting, excess sedation or the amount of time spent asleep at night.
1994

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

160-3.

Issue

2

Volume

72

Citation

Doyle E; Mottart KJ; Marshall C; Morton NS, “Comparison of different bolus doses of morphine for patient-controlled analgesia in children,” Pediatric Palliative Care Library, accessed October 18, 2021, https://pedpalascnetlibrary.omeka.net/items/show/12046.

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