Beta-endorphin and cholecystokinin 8 concentrations in peripheral blood mononuclear cells of autistic children

Title

Beta-endorphin and cholecystokinin 8 concentrations in peripheral blood mononuclear cells of autistic children

Creator

Brambilla F; Guareschi-Cazzullo A; Tacchini C; Musetti C; Panerai AE; Sacerdote P

Identifier

Publisher

Neuropsychobiology

Date

1997

Subject

Child; Female; Humans; Male; Reference Values; adolescent; Preschool; infant; beta-Endorphin/blood; Biomarkers of Pain; Child Development Disorders; Sincalide/blood; Monocytes/metabolism; Autistic Disorder/blood/diagnosis/psychology; Pervasive/blood/diagnosis/psychology

Description

beta-Endorphin (beta-EP) and cholecystokinin 8 (CCK-8) concentrations in peripheral blood mononuclear cells were measured in 12 drug-free autistic (AU) children, in 10 drug-free children with pervasive developmental disorders (PDD) and in 11 healthy controls. The aim of the study was to see whether or not there was an alteration of beta-EP and CCK-8 concentrations in this peripheral compartment, in which it has been suggested that secretion and regulation of the two peptides mimic those of neurons in the central nervous system. Mean beta-EP values were significantly higher in AU than in PDD and control children, while there were no differences in CCK-8 values of the three groups.
1997

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

1-4

Issue

1

Volume

35

Citation

Brambilla F; Guareschi-Cazzullo A; Tacchini C; Musetti C; Panerai AE; Sacerdote P, “Beta-endorphin and cholecystokinin 8 concentrations in peripheral blood mononuclear cells of autistic children,” Pediatric Palliative Care Library, accessed October 28, 2021, https://pedpalascnetlibrary.omeka.net/items/show/11880.

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