Acute drug prescribing to children on chronic antiepilepsy therapy and the potential for adverse drug interactions in primary care

Acute drug prescribing to children on chronic antiepilepsy therapy and the potential for adverse drug interactions in primary care

Novak PH; Ekins-Daukes S; Simpson CR; Milne RM; Helms P; McLay JS

British Journal of Clinical Pharmacology

2005

PedPal Lit; 11; 2-4; 22; 26; 5-11; Adolescent Anticonvulsants/administration & dosage/adverse effects Child Child; and 12-17-year-old age groups; and 12-17-year-olds; and 33/1000 children chronically prescribed antiepileptic therapy in the 0-1; and six for the 0-1; ciprofloxacin; Computerized Polypharmacy Prescriptions; Drug/statistics & numerical data Primary Health Care/statistics & numerical data Research Support; erythromycin; Newborn Medical Records Systems; Non-U.S. Gov't Scotland%X AIMS: To investigate the extent of acute coprescribing in primary care to children on chronic antiepileptic therapy; Preschool Drug Administration ScheduleDrug Interactions Epilepsy/drug therapy Humans Infant Infant; respectively. Of these acute coprescriptions 72 (1.5%) prescribed to 22 (3.0%) children were identified as a potential source of clinically serious interactions. The age-adjusted prevalence rates for potentially serious coprescribing were 86; respectively. The drugs most commonly coprescribed which could give rise to such interactions were antacids; six; theophylline and (TRUNCATED); with carbamazepine

2005

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