Predictors of Symptoms and Site of Death in Pediatric Palliative Patients With Cancer at End of Life

Title

Predictors of Symptoms and Site of Death in Pediatric Palliative Patients With Cancer at End of Life

Creator

Schindera C; Tomlinson D; Bartels U; Gillmeister Biljana; Alli A; Sung L

Publisher

The American Journal Of Hospice & Palliative Care

Date

2013

Subject

end of life; decision making; cancer; site of death; treatment choice

Description

OBJECTIVE: To describe how preferences and treatment influence symptoms at end of life and site of death in pediatric cancer. METHODS: We included 61 pediatric palliative patients with cancer whose parents previously participated in a study that elicited preferences for aggressive chemotherapy versus supportive care alone and who subsequently died. Main outcomes were severe pain and dyspnea proximal to death and site of death. RESULTS: Choice of aggressive chemotherapy predicted significantly more severe pain (odds ratio [OR] 3.1, 95% confidence interval [CI] 1.0-9.6; P = .049). Intravenous chemotherapy 4 weeks before death predicted severe dyspnea (OR 15.8, 95% CI 3.7-67.5; P < .001) and death outside the home (OR 0.3, 95% CI 0.1-0.9; P = .038). CONCLUSIONS: Parental choice of aggressive chemotherapy and more aggressive treatment proximal to death predicted more pain, dyspnea, and death in hospital. Strategies to improve quality of life are needed.
2013-07

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

548-552

Issue

5

Volume

31

Citation

Schindera C; Tomlinson D; Bartels U; Gillmeister Biljana; Alli A; Sung L, “Predictors of Symptoms and Site of Death in Pediatric Palliative Patients With Cancer at End of Life,” Pediatric Palliative Care Library, accessed July 28, 2021, https://pedpalascnetlibrary.omeka.net/items/show/14685.

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