Neuromuscular disorders of childhood

Neuromuscular disorders of childhood

Andersson PB; Rando TA

Current Opinion In Pediatrics

1999

Child; Diagnosis; Differential; Human; Neuromuscular Diseases/diagnosis/physiopathology/therapy; Charcot-Marie-Tooth Disease/diagnosis/physiopathology; Muscular Dystrophies/diagnosis/genetics; Myasthenia Gravis/diagnosis; Peripheral Nervous System Diseases/diagnosis; Spinal Muscular Atrophies of Childhood/diagnosis

Neuromuscular disorders are common causes of weakness and hypotonia in the infantile period and in childhood. Accurate diagnosis of specific neuromuscular disorders depends first on identification of which aspect of the peripheral neuromuscular system is affected--the motor neuron in the spinal cord, the nerve root or peripheral nerve, the neuromuscular junction, or the muscle--and then on the determination of the etiology and specific clinical entity. This review provides an overview of the major neuromuscular disorders of childhood with attention to recent advances and emerging areas of research.

1999

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