Can Parents Refuse A Potentially Lifesaving Transplant For Severe Combined Immunodeficiency?

Title

Can Parents Refuse A Potentially Lifesaving Transplant For Severe Combined Immunodeficiency?

Creator

Andrew S Nickels; G Douglas Myers; Liza-Marie Johnson; Avni Joshi; Richard R Sharp; Lantos J

Publisher

Pediatrics

Date

2016

Subject

Pediatrics; Life-saving Apparatus; Severe Combined Immunodeficiency; Research; Parents; Analysis; Methods

Description

If untreated, most children with severe combined immunodeficiency disorder (SCID) will die of complications of infection within the first 2 years of life. Early hematopoietic stem cell transplant (HSCT) is the current standard of care for this disease. Although potentially lifesaving, prognosis of HSCT in SCID is variable depending on a number of host and donor factors. Of the survivors, many develop secondary problems such as chronic graft-versus-host disease or even second malignancies. Posttransplant care is complex and requires great effort from parents to adhere to difficult treatment regimens. In this article, we address the difficult ethical question of what to do if parents choose not to have their child with SCID undergo HSCT but prefer palliative care.

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Citation List Month

July 2016 List

Citation

Andrew S Nickels; G Douglas Myers; Liza-Marie Johnson; Avni Joshi; Richard R Sharp; Lantos J, “Can Parents Refuse A Potentially Lifesaving Transplant For Severe Combined Immunodeficiency?,” Pediatric Palliative Care Library, accessed May 29, 2024, https://pedpalascnetlibrary.omeka.net/items/show/10515.