Efficacy and safety of paediatric medicinal cannabis use: A scoping review

Title

Efficacy and safety of paediatric medicinal cannabis use: A scoping review

Creator

Pawliuk C; Chau B; Rassekh SR; McKellar T; Siden H

Identifier

Publisher

Paediatrics and Child Health

Date

2021

Subject

Cannabidiol; Cannabis; Drug-resistant epilepsy; Medicinal marijuana; Scoping review; Tetrahydrocannabinoid; Medicinal Cannabis

Description

INTRODUCTION: The use of medicinal cannabis in the paediatric age group is increasing despite the lack of evidence for its efficacy or safety. OBJECTIVE: To map the available evidence on the efficacy and safety of medicinal cannabis in children and adolescents. METHODS: We conducted a scoping review and searched six electronic databases and grey literature. A study was eligible for inclusion when it investigated the efficacy or safety of medicinal cannabis for any condition, more than half of the participants were 0 to 18 years old, and had any study design except single case reports. RESULTS: We included 36 studies in our final analysis, 32 of which investigated the efficacy or safety of cannabis in treatment-resistant epilepsy. The remaining 4 studies examined patients with cancer, dysautonomia, Epidermolysis Bullosa, and motor disorders. CONCLUSIONS: There is a lack of evidence on the efficacy and safety of medicinal cannabis in most paediatric conditions.

Rights

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Citation

Pawliuk C; Chau B; Rassekh SR; McKellar T; Siden H, “Efficacy and safety of paediatric medicinal cannabis use: A scoping review,” Pediatric Palliative Care Library, accessed July 14, 2024, https://pedpalascnetlibrary.omeka.net/items/show/19011.