Risk factors associated with death in Brazilian children with severe dengue: a case-control study

Title

Risk factors associated with death in Brazilian children with severe dengue: a case-control study

Creator

dos Remedios Freitas Carvalho Branco Maria; de Albuquerque Luna Expedito Jose; Braga Junior LL; de Oliveira Ricardo Villar Barbosa; Rios Livia Teresa Moreira; do Socorro da Silva M; Medeiros Maria Nilza Lima; Silva GF; Nina Fernanda Campos Amaral Figueiredo; Lima Taliane Jardim; Brito JA; de Oliveira Avessandra Costa Cardoso; Pannuti CS

Publisher

Clinics

Date

2014

Description

OBJECTIVE: The purpose of this case-control study was to evaluate risk factors associated with death in children with severe dengue. METHODS: The clinical condition of hospitalized patients with severe dengue who died (cases, n = 18) was compared with that of hospitalized patients with severe dengue who survived (controls, n = 77). The inclusion criteria for this study were age under 13 years; hospital admission in São Luis, northeastern Brazil; and laboratory-confirmed diagnosis of dengue. RESULTS: Severe bleeding (hemoptysis), a defining criterion for dengue severity, was the factor most strongly associated with death in our study. We also found that epistaxis and persistent vomiting, both included as warning signs in the World Health Organization (WHO) classification of dengue, were strongly associated with death. No significant association was observed between any of the laboratory findings and death. CONCLUSIONS: The finding that epistaxis and persistent vomiting were also associated with death in children with severe dengue was unexpected and deserves to be explored in future studies. Because intensive care units are often limited in resource-poor settings, any information that can help to distinguish patients with severe dengue with a higher risk to progress to death may be crucial.
2014-01

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

55-60

Issue

1

Volume

69

Citation

dos Remedios Freitas Carvalho Branco Maria; de Albuquerque Luna Expedito Jose; Braga Junior LL; de Oliveira Ricardo Villar Barbosa; Rios Livia Teresa Moreira; do Socorro da Silva M; Medeiros Maria Nilza Lima; Silva GF; Nina Fernanda Campos Amaral Figueiredo; Lima Taliane Jardim; Brito JA; de Oliveira Avessandra Costa Cardoso; Pannuti CS, “Risk factors associated with death in Brazilian children with severe dengue: a case-control study,” Pediatric Palliative Care Library, accessed October 24, 2021, https://pedpalascnetlibrary.omeka.net/items/show/14788.

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