Strong opioids in pediatric palliative medicine

Strong opioids in pediatric palliative medicine

Hain RD; Miser A; Devins M; Wallace WH

Paediatr Drugs

2005

PedPal Lit; Analgesics; early research in children does suggest some significant differences in opioid pharmacokinetics; illustrated by the WHO guidelines; is essential for the adequate management of pain complicating the palliative phase in children with life-limiting conditions.; much of what has been published regarding the management of pain in palliative medicine in adults can be extrapolated. On saying that; Opioid/administration & dosage/adverse effects/therapeutic use Child Child; particularly with respect to morphine clearance; Preschool Half-Life Humans InfantMorphine/adverse effects/pharmacokinetics/therapeutic use Pain/classification/drug therapy Palliative Care/methods Tissue Distribution; the use of opioids in pediatric palliative care presents some unique challenges. Confident and rational use of o pioids by pediatricians; unsuitable for use in children; which seems to be faster in adults. Thus

2005

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