Priorities for Nutrition Research in Pediatric Critical Care

Priorities for Nutrition Research in Pediatric Critical Care

Tume L N; Valla F V; Floh A A; Goday P; Jotterand Chaparro C; Larsen B; Lee J H; Moreno Y M F; Pathan N; Verbruggen S; Mehta N M

Journal of Parenteral and Enteral Nutrition

2019

child; Child; Child Nutrition Disorders/prevention & control/*therapy; Child Nutritional Physiological Phenomena; Children; Consensus; Critical Care/*methods; Critical Illness; Delphi Technique; enteral nutrition; Humans; Intensive Care; Intensive care units (paediatric); Internationality; Nutritional Support/*methods; parenteral nutrition; Pediatric; research

BACKGROUND: Widespread variation exists in pediatric critical care nutrition practices, largely because of the scarcity of evidence to guide best practice recommendations. OBJECTIVE: The objective of this paper was to develop a list of topics to be prioritized for nutrition research in pediatric critical care in the next 10 years. METHODS: A modified 3-round Delphi process was undertaken by a newly established multidisciplinary group comprising 11 international researchers in the field of pediatric critical care nutrition. Items were ranked on a 5-point Likert scale. RESULTS: Forty-five research topics (with a mean priority score >3(0-5) were identified within the following 10 domains: the pathophysiology and impact of malnutrition in critical illness; nutrition assessment: nutrition risk assessment and biomarkers; accurate assessment of energy requirements in all phases of critical illness; the role of protein intake; the role of pharmaco-nutrition; effective and safe delivery of enteral nutrition; enteral feeding intolerance: assessment and management; the role of parenteral nutrition; the impact of nutrition status and nutrition therapies on long-term patient outcomes; and nutrition therapies for specific populations. Ten top research topics (that received a mean score >4(0-5) were identified as the highest priority for research. CONCLUSIONS: This paper has identified important consensus-derived priorities for clinical research in pediatric critical care nutrition. Future studies should determine topics that are a priority for patients and parents. Research funding should target these priority areas and promote an international collaborative approach to research in this field, with a focus on improving relevant patient outcomes.

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