Melatonin treatment for sleep disorders in children with neurodevelopmental disorders: an observational study

Title

Melatonin treatment for sleep disorders in children with neurodevelopmental disorders: an observational study

Creator

Ross C; Davies P; Whitehouse W

Publisher

Developmental Medicine and Child Neurology

Date

2002

Subject

Male; Nervous System Diseases; Medical Records; Nervous System Diseases/complications; Sex Factors; Dose-Response Relationship Drug; Child; Humans; Adolescent; Female; Child Preschool; Infant; Developmental Disabilities; Epilepsy/complications; Epilepsy; Outpatients; Vision Disorders/complications; Developmental Disabilities/complications; Melatonin/therapeutic use; Sleep Disorders/complications/drug therapy; Q3 Literature Search; Melatonin; Sleep Wake Disorders; child; female; male; Vision Disorders; sleep disturbance/disorders; Lennox-Gastaut syndrome; leukodystrophy; MPSII; MPSIII; pharmacologic intervention; melatonin

Description

The study aim was to quantify melatonin-associated improvement in sleep by means of a parent-completed sleep diary during routine outpatient activity. An investigation into sleep disturbance was made at neurology outpatient appointments. Those parents who identified a problem were asked to complete a sleep diary, after which treatment was initiated. The first week of the diary was completed before treatment, the second when established on the maximum dose of melatonin required. Forty-nine patients (26 males, 23 females) aged from one to 13 years, were treated between 1997 and 1998: 28 of these returned interpretable diaries. In a further 18 patients, an assessment could be made of the usefulness of the treatment. Patients were fairly typical of those attending a tertiary centre, the most common primary diagnosis being epilepsy (n=26). Only seven patients were visually impaired. Of the 46 patients who were assessed, 34 showed an improvement. No adverse effects were attributed to the treatment.

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Citation

Ross C; Davies P; Whitehouse W, “Melatonin treatment for sleep disorders in children with neurodevelopmental disorders: an observational study,” Pediatric Palliative Care Library, accessed October 23, 2021, https://pedpalascnetlibrary.omeka.net/items/show/16797.

Social Bookmarking