Sleep in individuals with Cri du Chat syndrome: a comparative study

Sleep in individuals with Cri du Chat syndrome: a comparative study

Maas A P; Didden R; Korzilius H; Braam W; Smits M G; Curfs L M

Journal of Intellectual Disability Research

2009

Middle Aged; Male; Infant Newborn; Severity of Illness Index; Statistics Nonparametric; Young Adult; Surveys and Questionnaires; Child; Humans; Adult; Adolescent; Prevalence; Female; Child Preschool; Infant; Cri-du-Chat Syndrome/ep [Epidemiology]; Sleep Wake Disorders/di [Diagnosis]; Sleep Wake Disorders/ep [Epidemiology]; Cri-du-Chat Syndrome/ge [Genetics]; Genetic Testing; sleep disturbance/disorders; Cri-du-chat; trajectory; characteristics

BACKGROUND: Sleep problems are common in individuals with intellectual disability. Little is known about sleep in children and adults with Cri du Chat syndrome (CDC).;METHOD: Sleep was investigated in 30 individuals with CDC using a sleep questionnaire. Sleep problems and sleep behaviours in individuals with CDC were compared with individuals with non-specific intellectual disabilities (NS) (n = 30) and Down's syndrome (DS) (n = 30).;RESULTS: Nine individuals with CDC (i.e. 30%) had a sleep problem, compared with seven individuals with NS (i.e. 23%) and three individuals with DS (i.e. 10%). Though there were few differences between diagnostic groups, night waking problems were most common in CDC. Individuals with CDC frequently showed behaviours related to disordered breathing and poor-quality sleep. Several behaviours related to sleep had a higher occurrence in CDC than in DS (P < 0.05) but not in NS.;CONCLUSIONS: It is concluded that individuals with CDC do not have an increased probability of sleep problems as compared with other individuals who share similar demographic characteristics. Hypotheses about causes of night waking problems in CDC are generated and suggestions for future research of sleep in individuals with CDC are given.

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).