Correlates of maladaptive behavior in individuals with 5p- (cri du chat) syndrome

Title

Correlates of maladaptive behavior in individuals with 5p- (cri du chat) syndrome

Creator

Dykens E M; Clarke D J

Publisher

Developmental Medicine and Child Neurology

Date

1997

Subject

Male; Surveys and Questionnaires; Child; Humans; Adult; Adolescent; Female; Child Preschool; Analysis of Variance; Risk Factors; Psychiatric Status Rating Scales; Adjustment Disorders/etiology; Child Behavior Disorders/etiology; Cri-du-Chat Syndrome/genetics/psychology; Gene Deletion; Intellectual Disability/psychology; Mental Disorders/etiology; Translocation Genetic; behavioral problems; Cri-du-chat; trajectory; characteristics; self-injury; aggression; pain behaviors; mood; low mood; hyperactivity; impulsivity; repetitive language use

Description

This study examined the range, distinctiveness, and correlates of maladaptive behavior in 146 subjects with 5p- (cri du chat) syndrome using the Aberrant Behavior Checklist as a standardized measure. Hyperactivity was the most significant and frequent problem in the sample. Subjects with 5p- syndrome also showed aggression, tantrums, self-injurious behavior, and stereotypies; some of these problems were more pronounced in individuals with lower cognitive-adaptive levels, as well as in those with histories of previous medication trials. Autistic-like features and social withdrawal were more characteristic of individuals with translocations as opposed to deletions, even when controlling for the lower adaptive level of the translocation group. These findings encourage further research on the behavior of individuals with 5p- syndrome.

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Citation

Dykens E M; Clarke D J, “Correlates of maladaptive behavior in individuals with 5p- (cri du chat) syndrome,” Pediatric Palliative Care Library, accessed October 19, 2021, https://pedpalascnetlibrary.omeka.net/items/show/16642.

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