International Cooperative Ataxia Rating Scale (ICARS): Appropriate for studies of Friedreich's ataxia?

Title

International Cooperative Ataxia Rating Scale (ICARS): Appropriate for studies of Friedreich's ataxia?

Creator

Cano S J; Hobart J C; Hart P E; Korlipara L V P; Schapira A H V; Cooper J M

Identifier

Publisher

Movement Disorders

Date

2005

Subject

tone and motor problems; friedreich's ataxia; tool development; scale development

Description

Clinicians require scientifically rigorous, clinically meaningful rating scales to evaluate the health impact of disease and treatment that cannot be measured using conventional laboratory instruments. This study evaluated the psychometric properties of the International Cooperative Ataxia Rating Scale (ICARS), a commonly used clinician-rated measure, in Friedreich's ataxia (FRDA). People with confirmed FRDA were assessed by using the ICARS. Two assumptions of its measurement model were tested: the legitimacy of reporting IC-ARS scores in FRDA, and the acceptability, reliability, and validity of total and subscale scores. Seventy-seven people with FRDA were assessed. The ICARS total score effectively satisfied all psychometric criteria tested. The posture and gait disturbances subscale also performed well. The other three subscales did not pass standard criteria for tests of scaling assumptions, reliability, and validity. This small study recommends only the use of the ICARS total score as a measure of FRDA. However, the extent to which this score quantifies the true extent of FRDA remains uncertain as our validity testing was limited, partly by the lack of appropriate validating measures. Further validity testing, and examination of responsiveness, is required before the ICARS can be recommended as an outcome measure for treatment trials of FDRA. © 2005 Movement Disorder Society.

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Citation

Cano S J; Hobart J C; Hart P E; Korlipara L V P; Schapira A H V; Cooper J M, “International Cooperative Ataxia Rating Scale (ICARS): Appropriate for studies of Friedreich's ataxia?,” Pediatric Palliative Care Library, accessed October 16, 2021, https://pedpalascnetlibrary.omeka.net/items/show/16604.

Social Bookmarking