Sleep disorders in tuberous sclerosis: a polysomnographic study

Title

Sleep disorders in tuberous sclerosis: a polysomnographic study

Creator

Bruni O; Cortesi F; Giannotti F; Curatolo P

Publisher

Brain and Development

Date

1995

Subject

Circadian Rhythm; Male; Child; Humans; Adolescent; Female; Child Preschool; Epilepsy; Tuberous Sclerosis; Polysomnography; Sleep Wake Disorders; sleep disturbance/disorders; trajectory; characteristics

Description

Overnight polysomnography was performed in 10 subjects with tuberous sclerosis (TS) and partial epilepsy in order to investigate the relationships between sleep organization, sleep disorders and epilepsy. Sleep architecture abnormalities were observed in 9 cases. Compared with ten healthy age-matched controls, the TS group showed a shorter total sleep time, a reduced sleep efficiency, a higher number of awakenings and stage transitions, an increased wake after sleep onset and stage 1 and a decreased REM sleep. Children with seizures showed a more disrupted sleep architecture compared with seizure-free children. Sleep disorders in TS were mainly due to sleep-related epileptic events and were more evident in children who showed large bifrontal or temporal tubers on MRI.

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Citation

Bruni O; Cortesi F; Giannotti F; Curatolo P, “Sleep disorders in tuberous sclerosis: a polysomnographic study,” Pediatric Palliative Care Library, accessed May 25, 2022, https://pedpalascnetlibrary.omeka.net/items/show/16597.

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