Causes and palliation of transfusion-associated vaginal bleeding in patients with metastatic cancer

Title

Causes and palliation of transfusion-associated vaginal bleeding in patients with metastatic cancer

Creator

Jackson AE; Stephens EK; Jatoi A

Publisher

International Journal Of Gynecological Cancer

Date

2014

Subject

adolescent; Female; Humans; retrospective studies; Young Adult; Palliative Care; Neoplasms; Adult; Aged; Middle Aged; Treatment Outcome; Neoplasm Metastasis; Uterine Hemorrhage

Description

PURPOSE: The current study was undertaken (1) to capture a clinically relevant, systematically collected series of patients with metastatic cancer and transfusion-associated vaginal bleeding and (2) to provide insight into how best to palliate this bleeding. METHODS/RESULTS: As part of a single-institution review, 46 patients with metastatic cancer and transfusion-associated vaginal bleeding were identified. In a minority, 14 (30%), the cancer itself was directly responsible for the bleeding, and under these circumstances, gynecological cancer was the most frequent cause. In 13 patients (28%), more than 1 palliative intervention was attempted. Of all the interventions, a hysterectomy was performed most frequently and was successful in 11 patients. The use of ablation or embolization procedures was rarely tried but successful in 4 patients. However, 2 patients died of vaginal bleeding, despite multiple palliative procedures to control bleeding, including tumor embolization in one. CONCLUSIONS: Transfusion-associated vaginal bleeding in patients with metastatic cancer can arise from nonmalignant causes and often assumes an uneventful course but can, at times, be serious and difficult to control.
2014-01

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

172-175

Issue

1

Volume

24

Citation

Jackson AE; Stephens EK; Jatoi A, “Causes and palliation of transfusion-associated vaginal bleeding in patients with metastatic cancer,” Pediatric Palliative Care Library, accessed August 2, 2021, https://pedpalascnetlibrary.omeka.net/items/show/14983.

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