Severe amiodarone-induced hypothyroidism in an infant

Severe amiodarone-induced hypothyroidism in an infant

Trudel K; Sanatani S; Panagiotopoulos C

Pediatric Critical Care Medicine

2010

OBJECTIVE:: To report a case of postnatal, postoperative amiodarone-induced hypothyroidism in an infant with a congenital heart defect. DESIGN:: Case report and literature review. SETTING:: Pediatric intensive care unit at a freestanding tertiary care children's hospital. PATIENT:: At 7 wks of age, a female infant with a congenital heart defect was confirmed to have profound hypothyroidism after amiodarone administration for a postoperative cardiac arrhythmia. INTERVENTIONS:: ------. MEASUREMENTS AND MAIN RESULTS:: ------. CONCLUSIONS:: Given the potential adverse developmental consequences associated with hypothyroidism during infancy and early childhood, thyroid function tests should be carefully monitored in any infant treated with amiodarone.

2010

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