Components of Placebo Effect: Randomised Controlled Trial in Patients with Irritable Bowel Syndrome

Title

Components of Placebo Effect: Randomised Controlled Trial in Patients with Irritable Bowel Syndrome

Creator

Kaptchuk TJ; Kelley JM; Conboy LA; Davis RB; Kerr CE; Jacobson EE; Kirsch I; Schyner RN; Nam BH; Nguyen LT; Park M; Rivers AL; McManus C; Kokkotou E; Drossman DA; Goldman P; Lembo AJ; Spiegel; Harrington

Publisher

Bmj

Date

2008

Subject

Patients; Research; Physician patient relationships; Acupuncture Therapy - adverse effects; Acupuncture Therapy - methods; Clinical Trials; Irritable bowel syndrome; Irritable Bowel Syndrome - therapy; Placebo Effect

Description

Kaptchuk et al investigate whether placebo effects can experimentally be separated into the response to three components--assessment and observation, a therapeutic ritual, and a supportive patient-practitioner relationship--and then progressively combined to produce incremental clinical improvement in patients with irritable bowel syndrome. Results show that factors contributing to the placebo effect can be progressively combined in a manner resembling a graded dose escalation of component parts. Non-specific effects can produce statistically and clinically significant outcomes and the patient-practitioner relationship is the most robust component.
2008-05

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

999-1003

Issue

7651

Volume

336

Citation

Kaptchuk TJ; Kelley JM; Conboy LA; Davis RB; Kerr CE; Jacobson EE; Kirsch I; Schyner RN; Nam BH; Nguyen LT; Park M; Rivers AL; McManus C; Kokkotou E; Drossman DA; Goldman P; Lembo AJ; Spiegel; Harrington, “Components of Placebo Effect: Randomised Controlled Trial in Patients with Irritable Bowel Syndrome,” Pediatric Palliative Care Library, accessed September 21, 2021, https://pedpalascnetlibrary.omeka.net/items/show/13870.

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