Enteric nervous system and developmental abnormalities in childhood

Title

Enteric nervous system and developmental abnormalities in childhood

Creator

Paran TS; Rolle U; Puri P

Publisher

Pediatric Surgery International

Date

2006

Subject

Child; Humans; Animals; Gastrointestinal Motility/physiology; Neurons/physiology; Chromosome Aberrations; Ganglion Cysts/embryology; Gastrointestinal Tract/innervation; Glial Cell Line-Derived Neurotrophic Factors/physiology; Hirschsprung Disease/physiopathology; Nervous System Malformations/embryology/physiopathology; Neural Crest/embryology; Neurotransmitter Agents/physiology

Description

ENS consists of a complex network of neurons, organised in several plexuses, which interact by means of numerous neurotransmitters. It is capable of modulating the intestinal motility, exocrine and endocrine secretions, microcirculation and immune and inflammatory responses within the gastrointestinal tract, independent of the central nervous system. Though the embryological development of various plexuses are completed by mid-way of gestation, the maturation of neurons and nerve plexuses appear to continue well after birth. Therefore, any histological or functional abnormalities related to the gastrointestinal function must be investigated with the ongoing maturational processes in mind.
2006

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

945-959

Issue

12

Volume

22

Citation

Paran TS; Rolle U; Puri P, “Enteric nervous system and developmental abnormalities in childhood,” Pediatric Palliative Care Library, accessed May 25, 2022, https://pedpalascnetlibrary.omeka.net/items/show/13786.

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