The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis
Title
The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis
Creator
Riddle R; Ryser CN; Morton AA; Sampson JD; Browne RH; Punaro MG; Gatchel RJ
Publisher
Journal of Pediatric Psychology
Date
2006
Subject
Child; Female; Humans; Male; Follow-Up Studies; Health Status; Multivariate Analysis; quality of life; adolescent; Preschool; PedPal Lit; infant; Comparative Study; Arthritis; Anti-Inflammatory Agents; Antirheumatic Agents/adverse effects/therapeutic use; Glucocorticoids/adverse effects/therapeutic use; Juvenile Rheumatoid/drug therapy; Methotrexate/adverse effects/therapeutic use; Methylprednisolone/adverse effects/therapeutic use; Non-Steroidal/adverse effects/therapeutic use
Description
OBJECTIVE: To assess and compare the impact of medication treatments on health-related quality of life (HRQOL), family function, and medical status in children with juvenile idiopathic arthritis (JIA). METHODS: Fifty-seven children diagnosed with JIA were assessed by a pediatric rheumatologist and placed into one of three treatment groups: (1) non-steroidal anti-inflammatory; (2) methotrexate; or (3) steroids via IV methylprednisolone. Questionnaires were administered at baseline and 4-month follow-up. The attending pediatric rheumatologist provided additional medical information. RESULTS: Data document the impact of JIA on HRQOL, particularly on physical and pain domains. Steroid patients experienced improved HRQOL at follow-up relative to other groups, despite reporting more problems with side effects. CONCLUSION: These results demonstrate positive benefits of steroids in treating JIA children, despite the greatest incidence of adverse side effects.
2006
Rights
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
Journal Article
Citation List Month
Backlog
Citation
Riddle R; Ryser CN; Morton AA; Sampson JD; Browne RH; Punaro MG; Gatchel RJ, “The impact on health-related quality of life from non-steroidal anti-inflammatory drugs, methotrexate, or steroids in treatment for juvenile idiopathic arthritis,” Pediatric Palliative Care Library, accessed February 7, 2025, https://pedpalascnetlibrary.omeka.net/items/show/13215.