Short-term safety assessment in the use of intravenous zoledronic acid in children

Title

Short-term safety assessment in the use of intravenous zoledronic acid in children

Creator

Hogler W; Yap F; Little D; Ambler G; McQuade M; Cowell CT

Publisher

The Journal Of Pediatrics

Date

2004

Subject

Child; Female; Humans; Male; Follow-Up Studies; Time Factors; adolescent; Preschool; retrospective studies; Infusions; Intravenous; Fever/chemically induced; Nausea/chemically induced; Clodronate; Calcium/blood; Bone Resorption/metabolism/prevention & control; Creatinine/blood; Diphosphonates/administration & dosage/adverse effects; Imidazoles/administration & dosage/adverse effects; Pain/chemically induced; Phosphorus/blood; Urea/blood; Vomiting/chemically induced

Description

The clinical side effects of the potent new bisphosphonate zoledronic acid in children are unknown. In this study of 34 children with various bone disorders, the frequency of postinfusion flu-like illness, hypocalcemia, and hypophosphatemia was 85%, 74%, and 82%, respectively. No renal side effects were detected after up to 3 consecutive infusions.
2004

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

701-704

Issue

5

Volume

145

Citation

Hogler W; Yap F; Little D; Ambler G; McQuade M; Cowell CT, “Short-term safety assessment in the use of intravenous zoledronic acid in children,” Pediatric Palliative Care Library, accessed October 23, 2021, https://pedpalascnetlibrary.omeka.net/items/show/13044.

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