Short-term safety assessment in the use of intravenous zoledronic acid in children
Title
Short-term safety assessment in the use of intravenous zoledronic acid in children
Creator
Hogler W; Yap F; Little D; Ambler G; McQuade M; Cowell CT
Identifier
Publisher
The Journal Of Pediatrics
Date
2004
Subject
Child; Female; Humans; Male; Follow-Up Studies; Time Factors; adolescent; Preschool; retrospective studies; Infusions; Intravenous; Fever/chemically induced; Nausea/chemically induced; Clodronate; Calcium/blood; Bone Resorption/metabolism/prevention & control; Creatinine/blood; Diphosphonates/administration & dosage/adverse effects; Imidazoles/administration & dosage/adverse effects; Pain/chemically induced; Phosphorus/blood; Urea/blood; Vomiting/chemically induced
Description
The clinical side effects of the potent new bisphosphonate zoledronic acid in children are unknown. In this study of 34 children with various bone disorders, the frequency of postinfusion flu-like illness, hypocalcemia, and hypophosphatemia was 85%, 74%, and 82%, respectively. No renal side effects were detected after up to 3 consecutive infusions.
2004
Rights
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
Journal Article
Citation List Month
Backlog
URL Address
Citation
Hogler W; Yap F; Little D; Ambler G; McQuade M; Cowell CT, “Short-term safety assessment in the use of intravenous zoledronic acid in children,” Pediatric Palliative Care Library, accessed April 20, 2024, https://pedpalascnetlibrary.omeka.net/items/show/13044.