The efficacy and side effects of continuous infusion intravenous morphine (CIVM) for pain and symptoms due to advanced cancer

Title

The efficacy and side effects of continuous infusion intravenous morphine (CIVM) for pain and symptoms due to advanced cancer

Creator

Glare P; Walsh D; Groh E; Nelson KA

Publisher

The American Journal Of Hospice & Palliative Care

Date

2002

Subject

Female; Humans; Male; United States; Pain; Adult; Analgesics; Aged; Middle Aged; 80 and over; retrospective studies; Palliative Care/methods; Infusions; Intravenous; Opioid/administration & dosage/adverse effects; Intractable/drug therapy/etiology; Morphine/administration & Neoplasms/complications

Description

Morphine is the strong opioid of choice in the management of moderate-to-severe chronic cancer pain. The preferred route of administration is oral, in individually titrated doses, regularly scheduled around the clock We conducted a retrospective study of continuous intravenous morphine (CIVM) in a palliative medicine program in 107 consecutive patients. The results suggest CIVM is an effective, safe, and versatile method of morphine administration when used with a defined protocol. Efficacy was similar to that obtained by others with intravenous morphine sulfate and also for oral morphine. Safety was suggested by the low incidence of dose-limiting side effects, most of which responded to dose reduction. Particularly noteworthy was the flexibility of CIVM with dose reduction in 20 percent.
2002

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

343-350

Issue

5

Volume

19

Citation

Glare P; Walsh D; Groh E; Nelson KA, “The efficacy and side effects of continuous infusion intravenous morphine (CIVM) for pain and symptoms due to advanced cancer,” Pediatric Palliative Care Library, accessed July 2, 2022, https://pedpalascnetlibrary.omeka.net/items/show/12721.

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