Antiepileptic drug therapy for adults: when to initiate and how to choose

Title

Antiepileptic drug therapy for adults: when to initiate and how to choose

Creator

Sirven JI

Identifier

Publisher

Mayo Clinic Proceedings

Date

2002

Subject

Humans; Adult; Treatment Outcome; Risk Factors; Amines; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Non-U.S. Gov't; Research Support; Recurrence; Epilepsy/drug therapy; Carbamazepine/analogs & derivatives/therapeutic use; Fructose/analogs & derivatives/therapeutic use; Acetic Acids/adverse effects/therapeutic use; Anticonvulsants/adverse effects/therapeutic use; Isoxazoles/therapeutic use; Nipecotic Acids/therapeutic use; Piracetam/analogs & derivatives/therapeutic use; Propylene Glycols/adverse effects/therapeutic use; Triazines/adverse effects/therapeutic use

Description

Although antiepileptic drugs (AEDs) are commonly used to control and prevent seizures, their long-term use carries a considerable risk of morbidity. The decision to start AEDs is made once the risks of further seizures outweigh the risks of treatment. Despite a large body of literature on the subject, this common clinical issue perplexes many practitioners because of its neurologic, psychological, and, at times, legal implications. Adding to the confusion is the recent approval of several new AEDs. This article summarizes the current evidence to support individual clinical decisions regarding initiation of AEDs in adults and considers the use of AEDs as seizure prophylaxis. Recently approved AEDs are discussed to help the practitioner understand when to initiate and how to choose the appropriate AED for the patient with seizures.
2002

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

1367-1375

Issue

12

Volume

77

Citation

Sirven JI, “Antiepileptic drug therapy for adults: when to initiate and how to choose,” Pediatric Palliative Care Library, accessed December 3, 2021, https://pedpalascnetlibrary.omeka.net/items/show/12626.

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