Can we conquer pain?

Title

Can we conquer pain?

Creator

Scholz J; Woolf CJ

Publisher

Nature Neuroscience

Date

2002

Subject

Biomarkers of Pain; Analgesics/pharmacology; Receptors; Human; Animal; Signal Transduction/drug effects/physiology; Afferent Pathways/drug effects/metabolism/physiopathology; Cell Surface/drug effects/metabolism; Central Nervous System/drug effects/metabolism/physiopathology; Drug Design; Nociceptors/drug effects/metabolism; Pain/drug therapy/metabolism/physiopathology; Synaptic Transmission/drug effects/physiology

Description

Pain can be an adaptive sensation, an early warning to protect the body from tissue injury. By the introduction of hypersensitivity to normally innocuous stimuli, pain may also aid in repair after tissue damage. Pain can also be maladaptive, reflecting pathological function of the nervous system. Multiple molecular and cellular mechanisms operate alone and in combination within the peripheral and central nervous systems to produce the different forms of pain. Elucidation of these mechanisms is key to the development of treatments that specifically target underlying causes rather than just symptoms. This new approach promises to revolutionize pain diagnosis and management.
2002

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

1062-7

Volume

5 Suppl

Citation

Scholz J; Woolf CJ, “Can we conquer pain?,” Pediatric Palliative Care Library, accessed November 27, 2021, https://pedpalascnetlibrary.omeka.net/items/show/12582.

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