Risk of secondary bacterial infection in infants hospitalized with respiratory syncytial viral infection

Title

Risk of secondary bacterial infection in infants hospitalized with respiratory syncytial viral infection

Creator

Hall CB; Powell KR; Schnabel KC; Gala CL; Pincus PH

Publisher

The Journal Of Pediatrics

Date

1988

Subject

Child; Humans; Prospective Studies; Risk Factors; Preschool; infant; Anti-Bacterial Agents/therapeutic use; Bacterial Infections/etiology; Pneumonia/etiology; Respiratory Syncytial Viruses; Respiratory Tract Infections/complications/drug therapy; Respirovirus Infections/complications/drug therapy

Description

Because infants hospitalized with respiratory syncytial virus (RSV) infection frequently receive antibiotics, our study was undertaken to determine what the actual risk of secondary bacterial infections in patients with RSV infection is and what effect antibiotic treatment might have on the course of illness. In a 9-year prospective study of 1706 children hospitalized with acute respiratory illnesses, 565 children had documented RSV infections. A subsequent bacterial infection rarely developed in those with RSV lower respiratory tract disease. The rate of subsequent bacterial infection was 1.2% in the total group of children infected with RSV, and 0.6% in the 352 children who received no antibiotics. A significantly greater proportion (4.5%) of subsequent bacterial infections occurred in infants who received parenteral antibiotics (p = 0.01), and especially in a subgroup who received parenteral antibiotics for 5 or more days (11%, p less than 0.001). We conclude that the risk of secondary bacterial infection appears to be low for most infants with RSV infection. In a few infants given parenteral broad-spectrum antibiotics the risk may be greater, but whether this is related to the antibiotic therapy or to other risk factors is not clear.
1988

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Citation

Hall CB; Powell KR; Schnabel KC; Gala CL; Pincus PH, “Risk of secondary bacterial infection in infants hospitalized with respiratory syncytial viral infection,” Pediatric Palliative Care Library, accessed May 26, 2024, https://pedpalascnetlibrary.omeka.net/items/show/12529.