The use of oral methadone to control moderate and severe pain in children and young adults with malignancy

Title

The use of oral methadone to control moderate and severe pain in children and young adults with malignancy

Creator

Miser AW; Miser JS

Publisher

The Clinical Journal Of Pain

Date

1986

Subject

Child; Pain; Methadone; adolescent; Administration; Oral; Neoplasms

Description

Twenty-two courses of oral methadone were given to control moderate or severe pain in 19 children with cancer. Of these, 21 courses gave adequate pain control for periods of 5 to 267 days (median 24 days). In 16 courses, methadone was continued until death or until the pain resolved; in five remaining courses, a change to parenteral narcotics was ultimately required. Toxicity was minimal. A safe starting dose of methadone appears to be 0.1 mg/kg given every 4 hours, or the equivalent total daily dose given less frequently, with escalation as required to achieve and maintain adequate pain control.
1986

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

243-248

Volume

1

Citation

Miser AW; Miser JS, “The use of oral methadone to control moderate and severe pain in children and young adults with malignancy,” Pediatric Palliative Care Library, accessed May 19, 2022, https://pedpalascnetlibrary.omeka.net/items/show/12488.

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