Fasting associated with decrease in hypothalamic beta-endorphin

Fasting associated with decrease in hypothalamic beta-endorphin

Gambert SR; Garthwaite TL; Pontzer CH; Hagen TC

Science

1980

Male; Time Factors; Animals; Rats; Non-U.S. Gov't; Research Support; Fasting; Corticotropin/metabolism; Endorphins/metabolism; Hypothalamus/metabolism; Pituitary Gland/metabolism

In rats that were fasted for 2 to 3 days there was a decline in hypothalamic, but not pituitary, beta-endorphin. There was no change in pituitary or hypothalamic adrenocorticotropin content as a result of fasting. Endogenous opiates may be involved in physiological adaptation to fasting.

1980

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