High-dose oral morphine in cancer pain management: a report of twelve cases

Title

High-dose oral morphine in cancer pain management: a report of twelve cases

Creator

Radbruch L; Grond S; Zech DJ; Bischoff A

Publisher

Journal of Clinical Anesthesia

Date

1996

Subject

Female; Male; Pain; Analgesics; Aged; Fatal Outcome; Non-U.S. Gov't; Human; Case Report; Support; Intractable/drug therapy/etiology; Middle Age; Morphine/administration & dosage/adverse effects/therapeutic use; Neoplasms/complications; Opioid/administration & dosage/adverse effects/therapeutic; use

Description

We present 12 case reports from patients treated with more than 600 mg of morphine per day. We found no "opioid-nonresponsive pain" under treatment with a combination of morphine and nonopioids, supplemented with coanalgesics where appropriate. Side effects of morphine therapy were controlled with adjuvant drugs. Serious adverse effects were not observed. Episodes of break-through pain, dysphagia, and dyspnea caused by far advanced cancer disease were seen frequently.
1996

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Citation

Radbruch L; Grond S; Zech DJ; Bischoff A, “High-dose oral morphine in cancer pain management: a report of twelve cases,” Pediatric Palliative Care Library, accessed May 27, 2024, https://pedpalascnetlibrary.omeka.net/items/show/12278.