β-Endorphin, but not substance-P, is increased by acute stress in humans

Title

β-Endorphin, but not substance-P, is increased by acute stress in humans

Creator

Schedlowski M; Flüge T; Richter S; Tewes Uwe; Schmidt RE; Wagner Thomas OF

Publisher

Psychoneuroendocrinology

Date

1995

Subject

Anxiety; Stress; Locus of control; Substance-P; β-endorphin

Description

The role of neuropeptides in the psychoneuroendocrinological stress response is largely unknown. In this study the effect of acute psychological stress on β-endorphin and substance-P plasma concentrations was investigated and further the effect of different anxiety levels or control attributions on β-endorphin or substance-P levels was determined. Blood samples were obtained from 47 inexperienced tandem-parachutists 2 h before, immediately after, and 1 h after a parachute jump and plasma concentrations of β-endorphin and substance-P were analysed. Anxiety levels and control attributions were assessed by psychometric scales. Whereas substance-P concentrations seemed to be unaffected by the jump stress, there was a transient but significant increase in β-endorphin levels immediately after jumping. However, subjects higher in state-anxiety at the point of jumping (exit) displayed higher substance-P values at all three time points compared to the “low-anxiety” jumpers. In addition, stress-induced β-endorphin secretion was dependent on subjective control attributions.
1995

Rights

Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).

Type

Journal Article

Citation List Month

Backlog

Pages

103-110

Issue

1

Volume

20

Citation

Schedlowski M; Flüge T; Richter S; Tewes Uwe; Schmidt RE; Wagner Thomas OF, “β-Endorphin, but not substance-P, is increased by acute stress in humans,” Pediatric Palliative Care Library, accessed July 2, 2022, https://pedpalascnetlibrary.omeka.net/items/show/11606.

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