Subject
Adaptation; PedPal Lit; more methodologically rigorous trials using prospective longitudinal study designs with pre- and post-measures to examine all QOL domains in children.; one cross-sectional; practice and theory. The studies' methodological quality was evaluated separately by two investigators according to a set of formal criteria modified from Hoodin and Weber (Psychosomatics 44 (2003) 181). The review yielded one retrospective; PsychologicalAttitude to Health Bone Marrow Transplantation/adverse effects/psychology ChildChild Psychology Child Welfare Cross-Sectional Studies Data Collection Data Interpretation; psychometrically sound; QOL measure. Timing of assessments ranged from pre-BMT to 21 years following BMT. Due to the poor methodological quality; rendering conclusions across the studies was challenging. While the available evidence seems to suggest children experience good QOL following BMT; several studies found BMT to have a negative impact on various aspects of QOL. These results appear to be influenced by timing and type of measurements undertaken. Ultimately; six descriptive surveys and two prospective longitudinal study designs. The studies included 568 childhood BMT recipients ranging from 0.8 to 33 years. Only one study used a generic and disease-specific; Statistical Humans Mental Health Nursing Methodology Research Outcome Assessment (Health Care) Prospective Studies PsychometricsQuality of Life Research Design/standards Research Support; there is a need for larger