1
40
1
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/mus.25524" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/mus.25524</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Mitochondrial capacity, muscle endurance, and low energy in friedreich ataxia
Publisher
An entity responsible for making the resource available
Muscle and Nerve
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
Subject
The topic of the resource
adolescent; priority journal; scoring system; school child; cross-sectional study; fatigue; human; article; child; female; male; controlled study; adult; clinical article; comparative study; disease severity; Friedreich ataxia; cellular subcellular and molecular biological phenomena and functions; energy; physical energy; mitochondrial capacity; muscle exercise; electrostimulation; Godin Leisure Time Physical Activity Score; mechanomyography; myography; near infrared spectroscopy; oxygen consumption; skeletal muscle; trajectory; characteristics; endurance; muscle endurance; alertness
Creator
An entity primarily responsible for making the resource
Bossie H M; Willingham T B; Schoick R A V; O'Connor P J; McCully K K
Description
An account of the resource
Introduction: In this study we noninvasively evaluated skeletal muscle mitochondrial capacity, muscle-specific endurance, and energy/fatigue feelings in persons with Friedreich ataxia (FRDA) and able-bodied controls (AB). Methods: Forearm mitochondrial capacity was measured in FRDA (n = 16) and AB (n = 10) study participants using the rate of recovery of oxygen consumption after electrical stimulation with near-infrared spectroscopy. Mechanomyography (MMG) assessed muscle endurance after electrical stimulation for 3 minutes at 2 Hz, 4 Hz, and 6 Hz. Validated scales assessed disease severity and energy/fatigue feelings. Results: Groups did not differ in mitochondrial capacity (FRDA and AB: 1.8 +/- 0.3 L/min). The difference in muscle endurance at 6 Hz was lower by 19.2% in the FRDA group (group effect: P < 0.001). Feelings of physical energy were 34% lower in FRDA group. In FDRA muscle, endurance was positively related to mitochondrial capacity (r = 0.59, P = 0.03), and disease severity was negatively related to mitochondrial capacity (r = -0.55, P = 0.04) and muscle endurance (r = -0.60, P = 0.01). Conclusion: Non-invasive measures of skeletal muscle mitochondrial capacity and muscle-specific endurance are useful in monitoring FRDA. Muscle Nerve 56: 773-779, 2017.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1002/mus.25524" target="_blank" rel="noreferrer noopener">10.1002/mus.25524</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
Adolescent
Adult
alertness
Article
Bossie H M
cellular subcellular and molecular biological phenomena and functions
characteristics
Child
Clinical Article
Comparative Study
Controlled Study
Cross-sectional Study
Disease Severity
electrostimulation
endurance
energy
Fatigue
Female
Friedreich ataxia
Godin Leisure Time Physical Activity Score
Human
Male
McCully K K
mechanomyography
mitochondrial capacity
Muscle and Nerve
muscle endurance
muscle exercise
myography
near infrared spectroscopy
O'Connor P J
oxygen consumption
physical energy
Priority Journal
Schoick R A V
School Child
scoring system
skeletal muscle
Trajectory
Willingham T B