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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
October 2019 List
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
October 2019 List
URL Address
<a href="http://doi.org/10.1136/bmjpo-2019-000467" target="_blank" rel="noreferrer noopener">http://doi.org/10.1136/bmjpo-2019-000467</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Gabapentin for the treatment of pain manifestations in children with severe neurological impairment: A single-centre retrospective review
Publisher
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BMJ Paediatrics Open
Date
A point or period of time associated with an event in the lifecycle of the resource
2019
Subject
The topic of the resource
child; human; retrospective study; clinical article; palliative care; pain; priority journal; review; alopecia/si [Side Effect]; disease severity; drug efficacy; drug substitution; drug withdrawal; gabapentin/ae [Adverse Drug Reaction]; gabapentin/dt [Drug Therapy]; gabapentin/pv [Special Situation for Pharmacovigilance]; gastroenterology; general paediatrics; hypertransaminasemia/si [Side Effect]; irritability; lethargy/si [Side Effect]; muscle twitch; neurodisability; neurologic disease; pain/dt [Drug Therapy]; pregabalin/dt [Drug Therapy]; pregabalin/pv [Special Situation for Pharmacovigilance]; treatment duration; treatment response; vomiting/dt [Drug Therapy]; vomiting/si [Side Effect]
Creator
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Collins A; Mannion R; Broderick A; Hussey S; Devins M; Bourke B
Description
An account of the resource
Pain, irritability and feeding intolerance are common symptoms affecting quality of life in children with severe neurological impairment (SNI). We performed a retrospective study to explore the use of gabapentinoid medications for symptom control in children with SNI. Patients attending the palliative care or gastroenterology department being treated with gabapentin for irritability, vomiting or pain of unknown origin were included. Information was gathered retrospectively from medical documentation. Irritability was reduced in 30 of the 42 patients included. Gabapentin was discontinued in 15 children, 12 of whom then received pregabalin. Three children had a good response to pregabalin, six a minimal improvement and three no improvement. These results support the use of gabapentinoids in this patient cohort. Copyright © Author(s) (or their employer(s)) 2019.
Identifier
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<a href="http://doi.org/10.1136/bmjpo-2019-000467" target="_blank" rel="noreferrer noopener">10.1136/bmjpo-2019-000467</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2019
alopecia/si [Side Effect]
BMJ Paediatrics Open
Bourke B
Broderick A
Child
Clinical Article
Collins A
Devins M
Disease Severity
Drug Efficacy
Drug Substitution
Drug Withdrawal
gabapentin/ae [Adverse Drug Reaction]
gabapentin/dt [Drug Therapy]
gabapentin/pv [Special Situation for Pharmacovigilance]
Gastroenterology
General Paediatrics
Human
Hussey S
hypertransaminasemia/si [Side Effect]
Irritability
lethargy/si [Side Effect]
Mannion R
muscle twitch
Neurodisability
Neurologic Disease
October 2019 List
Pain
Pain/dt [drug Therapy]
Palliative Care
pregabalin/dt [Drug Therapy]
pregabalin/pv [Special Situation for Pharmacovigilance]
Priority Journal
Retrospective Study
Review
treatment duration
treatment response
vomiting/dt [Drug Therapy]
vomiting/si [Side Effect]