1
40
1
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1007/s00455-017-9804-4" target="_blank" rel="noreferrer noopener">http://doi.org/10.1007/s00455-017-9804-4</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Dysphagia in Friedreich Ataxia
Publisher
An entity responsible for making the resource available
Dysphagia
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
Subject
The topic of the resource
Quality of life; speech; management; Otorhinolaryngology; Swallowing; adults; Gait disorders/ataxia; interrater reliability; molecular-genetics; pathogenesis; pathology; penetration-aspiration scale; Trinucleotide repeat diseases; Videofluoroscopy; feeding difficulties; Friedreich's ataxia; trajectory; characteristics; dysphagia; penetration; aspiration
Creator
An entity primarily responsible for making the resource
Keage M J; Delatycki M B; Gupta I;Corben L A; Vogel A P
Description
An account of the resource
The objective of the study was to comprehensively characterise dysphagia in Friedreich ataxia (FRDA) and identify predictors of penetration/aspiration during swallowing. We also investigated the psychosocial impact of dysphagia on individuals with FRDA. Sixty participants with FRDA were screened for dysphagia using a swallowing quality of life questionnaire (Swal-QOL) and case history. Individuals reporting dysphagia underwent a standardised oromotor assessment (Frenchay Dysarthria Assessment, 2, FDA-2) and videofluoroscopic study of swallowing (VFSS). Data were correlated with disease parameters (age at symptom onset, age at assessment, disease duration, FXN intron 1 GAA repeat sizes, and Friedreich Ataxia Rating Scale (FARS) score). Predictors of airway penetration/aspiration were explored using logistic regression analysis. Ninety-eight percent (59/60) of participants reported dysphagia, of whom 35 (58.3%) underwent FDA-2 assessment, and 38 (63.3%) underwent VFSS. Laryngeal, respiratory, and tongue dysfunction was observed on the FDA-2. A Penetration-Aspiration Scale score above 3 (deemed significant airway compromise based on non-clinical groups) was observed on at least one consistency in 13/38 (34.2%) participants. All of those who aspirated (10/38, 26.3%) did so silently, with no overt signs of airway entry such as reflexive cough. Significant correlations were observed between dysphagic symptoms and disease duration and severity. No reliable predictors of penetration or aspiration were identified. Oropharyngeal dysphagia is commonly present in individuals with FRDA and worsens with disease duration and severity. Individuals with FRDA are at risk of aspiration at any stage of the disease and should be reviewed regularly. Instrumental analysis remains the only reliable method to detect aspiration in this population. Dysphagia significantly affects the quality of life of individuals with FRDA.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1007/s00455-017-9804-4" target="_blank" rel="noreferrer noopener">10.1007/s00455-017-9804-4</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2017
adults
aspiration
characteristics
Corben L A
Delatycki M B
Dysphagia
feeding difficulties
Friedreich's ataxia
Gait disorders/ataxia
Gupta I
interrater reliability
Keage M J
Management
molecular-genetics
Otorhinolaryngology
pathogenesis
Pathology
penetration
penetration-aspiration scale
Quality Of Life
Speech
Swallowing
Trajectory
Trinucleotide repeat diseases
Videofluoroscopy
Vogel A P