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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
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URL Address
<a href="http://doi.org/10.1212/WNL.56.9.1236" target="_blank" rel="noreferrer noopener">http://doi.org/10.1212/WNL.56.9.1236</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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A favorable response to antiparkinsonian treatment in juvenile neuronal ceroid lipofuscinosis
Publisher
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Neurology
Date
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2001
Subject
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tone and motor problems; NCL3; NCL6; pharmacologic intervention; levodopa; selegiline
Creator
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Aberg L E; Rinne J O; Rajantie I; Santavuori P
Description
An account of the resource
To study the effect of dopaminergic drugs on the parkinsonism in juvenile neuronal ceroid lipofuscinosis, the authors conducted an open study of 21 patients. According to the motor Unified PD Rating Scale (UPDRS) score, treatment was initiated with either levodopa (n = 10) or selegiline (n = 6). Five patients served as a control group. The UPDRS score after 1 year was compared with the score at onset. Both in the control group and in the selegiline group, the mean UPDRS score increased, whereas in the levodopa group, the mean UPDRS score decreased. The difference between the levodopa group and the control group was significant.
Identifier
An unambiguous reference to the resource within a given context
<a href="http://doi.org/10.1212/WNL.56.9.1236" target="_blank" rel="noreferrer noopener">10.1212/WNL.56.9.1236</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2001
Aberg L E
levodopa
NCL3
NCL6
Neurology
pharmacologic intervention
Rajantie I
Rinne J O
Santavuori P
selegiline
tone and motor problems
-
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
A name given to the resource
Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
URL Address
<a href="http://doi.org/10.1002/mds.23478" target="_blank" rel="noreferrer noopener">http://doi.org/10.1002/mds.23478</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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Levodopa is not a useful treatment for Lesch-Nyhan disease
Publisher
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Movement Disorders
Date
A point or period of time associated with an event in the lifecycle of the resource
2011
Subject
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behavior problems; tone and motor problems; Lesch-Nyhan syndrome; pharmacologic intervention; levodopa; levodopa-dopa; carbidopa
Creator
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Bloem B R; Schretlen D J; Jinnah H A; Visser J E
Description
An account of the resource
Lesch-Nyhan disease (LND) is characterized by dystonia, cognitive abnormalities, and self-injurious behavior. No effective therapies are available. LND is associated with a presynaptic dopaminergic deficit, but the reported effects of dopamine replacement therapy are conflicting. The current prospective open-label study assesses the effects of levodopa on both neurological and behavioral features of LND. All 6 study participants discontinued levodopa early, due to lack of effect and sometimes worsening of motor function. The results provide important clues for pathophysiological mechanisms and suggestions for future treatment options.Copyright © 2011 Movement Disorder Society.
Identifier
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<a href="http://doi.org/10.1002/mds.23478" target="_blank" rel="noreferrer noopener">10.1002/mds.23478</a>
Rights
Information about rights held in and over the resource
Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2011
behavior problems
Bloem B R
carbidopa
Jinnah H A
Lesch-Nyhan syndrome
levodopa
levodopa-dopa
Movement Disorders
pharmacologic intervention
Schretlen D J
tone and motor problems
Visser J E