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Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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2018 Oncology List
Text
A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text.
Citation List Month
Oncology 2018 List
URL Address
<a href="http://doi.org/10.18632/oncotarget.21188" target="_blank" rel="noreferrer noopener">http://doi.o
rg/10.18632/oncotarget.21188</a>
Dublin Core
The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/.
Title
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End-of-life care in children with hematologic malignancies
Publisher
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Oncotarget
Date
A point or period of time associated with an event in the lifecycle of the resource
2017
Subject
The topic of the resource
home care; adolescent; blood transfusion; retrospective study; 52-26-6 (morphine); 57-27-2 (morphine); prescription; cohort analysis; fatigue; morphine/dt [Drug Therapy]; patient referral; treatment duration; human; article; child; female; male; controlled study; adult; terminal care; clinical article; child care; palliative therapy; intensive care unit; walking difficulty; hematologic malignancy/dt [Drug Therapy]; hematologic malignancy/th [Therapy]; hematologic malignancy/dt [Drug Therapy]; hospital mortality; mucosa inflammation; pallor; petechia; somnolence
Creator
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Hoell JI; Warfsmann J; Balzer S; Borkhardt A; Janssen G; Kuhlen M
Description
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Introduction: Hematologic malignancies (HM) represent the most common neoplasms in childhood. Despite improved overall survival rates, they are still a major contributor to cancer death in children. Aims: To determine the proportion of children with HM in pediatric palliative care (PPC) and to identify the clinical characteristics and symptoms in comparison to children with extracranial solid tumors (non HM patients). Patients and Methods: This study was conducted as a single-center retrospective cohort study of patients in the care of a large specialized PPC team. Results: Fifteen HM and 50 non HM patients were included. Symptoms in which HM patients scored significantly higher than non HM patients were mucositis, difficulty moving, somnolence, fatigue, petechiae and paleness. Blood transfusions were more frequently administered to HM patients, but large external hemorrhage was not observed in any child. A large variety of drugs and appliances were needed by the patients, with morphine being the most frequently prescribed drug. During the study period, a much larger and over the years even increasing number of HM patients (not in the care of the PPC team) died in hospital with an (assumed) curative intent, with two thirds dying in the ICU. Conclusions: Children with HM were referred to outpatient PPC with almost the full clinical picture of advanced leukemia. Noteworthy, the number of children with HM dying at home is decreasing in our center, instead a substantial proportion received high-intensity medical hospital care including novel anticancer therapies. These patients thus seem to be at an increased risk of dying in hospital as the right time to transfer them to palliative care is oftentimes missed.
Identifier
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<a href="http://doi.org/%2010.18632/oncotarget.21188" target="_blank" rel="noreferrer noopener">10.18632/oncotarget.21188</a>
2017
52-26-6 (morphine)
57-27-2 (morphine)
Adolescent
Adult
Article
Balzer S
Blood Transfusion
Borkhardt A
Child
Child Care
Clinical Article
Cohort Analysis
Controlled Study
Fatigue
Female
hematologic malignancy/dt [Drug Therapy]
hematologic malignancy/th [Therapy]
Hoell JI
Home Care
Hospital Mortality
Human
Intensive Care Unit
Janßen G
Kuhlen M
Male
Morphine/dt [drug Therapy]
mucosa inflammation
Oncology 2018 List
Oncotarget
Palliative Therapy
pallor
Patient Referral
petechia
prescription
Retrospective Study
somnolence
Terminal Care
treatment duration
walking difficulty
Warfsmann J