1 40 1 Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource 2023 Special Edition 5 - Low Resource Setting List Text A resource consisting primarily of words for reading. Examples include books, letters, dissertations, poems, newspapers, articles, archives of mailing lists. Note that facsimiles or images of texts are still of the genre Text. Citation List Month 2023 SE5 - Low Resource Setting URL Address <a href="http://doi.org/10.1080/07357907.2022.2141771" target="_blank" rel="noreferrer noopener"> http://doi.org/10.1080/07357907.2022.2141771</a> Dublin Core The Dublin Core metadata element set is common to all Omeka records, including items, files, and collections. For more information see, http://dublincore.org/documents/dces/. Title A name given to the resource Real World Presentation and Treatment Outcomes with a Predominant Induction Chemotherapy Based Approach in Nasopharyngeal Carcinoma: A Sixteen Year Report from a Teaching Hospital in India Publisher An entity responsible for making the resource available Cancer Investigation Date A point or period of time associated with an event in the lifecycle of the resource 2023 Subject The topic of the resource child; adult; article; cohort analysis; female; human; major clinical study; male; retrospective study; aged; hospitalization; India; follow up; cancer recurrence; overall survival; adolescent; hearing impairment; diplopia; adjuvant therapy; smoking; multiple cycle treatment; overall response rate; progression free survival; thrombocytopenia; headache; diarrhea; histopathology; intensity modulated radiation therapy; anemia; vomiting; cancer staging; teaching hospital; palliative chemotherapy; carboplatin/cb [Drug Combination]; carboplatin/dt [Drug Therapy]; cisplatin/ae [Adverse Drug Reaction]; cisplatin/cb [Drug Combination]; cisplatin/dt [Drug Therapy]; gemcitabine/dt [Drug Therapy]; paclitaxel/cb [Drug Combination]; paclitaxel/dt [Drug Therapy]; treatment outcome; cyclophosphamide/cb [Drug Combination]; cyclophosphamide/dt [Drug Therapy]; mucosa inflammation; antiemetic agent; treatment interruption; date of death; survival prediction; neck dissection; hypothyroidism; induction chemotherapy; nasopharynx carcinoma/dt [Drug Therapy]; nasopharynx carcinoma/rt [Radiotherapy]; nasopharynx carcinoma/su [Surgery]; albumin/ec [Endogenous Compound]; bone metastasis; capecitabine/dt [Drug Therapy]; cervical lymph node; chemoradiotherapy; cisplatin/to [Drug Toxicity]; cobalt therapy; cranial nerve paralysis; distant metastasis; docetaxel/cb [Drug Combination]; docetaxel/dt [Drug Therapy]; dysphasia; epirubicin/cb [Drug Combination]; epirubicin/dt [Drug Therapy]; exophthalmos; febrile neutropenia; fluorouracil/cb [Drug Combination]; fluorouracil/dt [Drug Therapy]; liver metastasis; lung metastasis; neck swelling; neutropenia; nose obstruction; peripheral neuropathy; primary tumor/rt [Radiotherapy]; radiotherapy dosage; salvage therapy; spinal cord; toxicity/si [Side Effect]; trismus; xerostomia Creator An entity primarily responsible for making the resource Gogi R; Sharma A; Mohanti BK; Pramanik R; Bhasker S; Biswas A; Thakar A; Singh AC; Sikka K; Kumar R; Thulkar S; Bahadur S Description An account of the resource Introduction: Nasopharyngeal carcinoma (NPC) is a rare malignancy in India except in north-eastern states. We present our institutional experience of 16 years highlighting management, outcomes, responses and toxicities. Material(s) and Method(s): NPC patients registered at our center during the period of 2000-2015. The primary objective of the study was to assess the overall survival (OS). Secondary outcome included determinations of response rates, progression free survival (PFS) and to assess treatment-related toxicity (CTCAE v4.0). Institute ethics committee approval was obtained prior to initiation of this study. Result(s): Data was retrieved from complete records of 222 patients out of 390 registered during study period. There were 163 males (73.4%) and 59 females (26.6%) with a male to female ratio of 2.8:1. The median age was 35 years (range 6-73). Only 5.6% (n = 12) presented in early-stage disease (stage I and II) while 89.6% (n = 199) were advanced stage (stage III, IVA, IVB). Five patients (2.2%) presented as metastatic disease. Majority of patients were treated with induction chemotherapy followed by concurrent chemoradiation (CCRT) {76.1%, n = 169}. Relapses were documented in 10.4% patients. 5% patients had loco-regional relapse while distant metastases were seen in 4% patients. The 3-year PFS and OS rates are 60.9% and 68.4%, respectively. Achieving a CR predicted superior OS on multivariate analysis. Conclusion(s): NPC is a rare malignancy and majority presented with advanced stages. This data outlines our experience and outcomes with a predominantly induction chemotherapy followed by definitive CCRT based approach.Copyright © 2022 Taylor & Francis Group, LLC. Identifier An unambiguous reference to the resource within a given context <a href="http://doi.org/10.1080/07357907.2022.2141771" target="_blank" rel="noreferrer noopener">10.1080/07357907.2022.2141771</a> Rights Information about rights held in and over the resource Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s). 2023 2023 SE5 - Low Resource Setting adjuvant therapy Adolescent Adult Aged albumin/ec [Endogenous Compound] Anemia antiemetic agent Article Bahadur S Bhasker S Biswas A bone metastasis Cancer Investigation Cancer Recurrence Cancer Staging capecitabine/dt [Drug Therapy] carboplatin/cb [Drug Combination] carboplatin/dt [Drug Therapy] cervical lymph node chemoradiotherapy Child cisplatin/ae [Adverse Drug Reaction] cisplatin/cb [Drug Combination] cisplatin/dt [Drug Therapy] cisplatin/to [Drug Toxicity] cobalt therapy Cohort Analysis cranial nerve paralysis cyclophosphamide/cb [Drug Combination] cyclophosphamide/dt [Drug Therapy] date of death Diarrhea diplopia distant metastasis docetaxel/cb [Drug Combination] docetaxel/dt [Drug Therapy] dysphasia epirubicin/cb [Drug Combination] epirubicin/dt [Drug Therapy] exophthalmos febrile neutropenia Female fluorouracil/cb [Drug Combination] fluorouracil/dt [Drug Therapy] Follow Up gemcitabine/dt [Drug Therapy] Gogi R Headache hearing impairment Histopathology Hospitalization Human hypothyroidism India induction chemotherapy Intensity Modulated Radiation Therapy Kumar R liver metastasis lung metastasis Major Clinical Study Male Mohanti BK mucosa inflammation multiple cycle treatment nasopharynx carcinoma/dt [Drug Therapy] nasopharynx carcinoma/rt [Radiotherapy] nasopharynx carcinoma/su [Surgery] neck dissection neck swelling Neutropenia nose obstruction overall response rate Overall Survival paclitaxel/cb [Drug Combination] paclitaxel/dt [Drug Therapy] palliative chemotherapy peripheral neuropathy Pramanik R primary tumor/rt [Radiotherapy] progression free survival Radiotherapy Dosage Retrospective Study Salvage Therapy Sharma A Sikka K Singh AC Smoking Spinal cord survival prediction teaching hospital Thakar A thrombocytopenia Thulkar S toxicity/si [Side Effect] treatment interruption Treatment Outcome trismus Vomiting xerostomia