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Lesch-Nyhan syndrome is a rare, sex-linked, recessive disease that is accompanied by severe self-mutilation, especially finger biting. Evidence is presented suggesting that parental response patterns may contribute to the genesis of the…

The self injurious behavior of five male children with Lesch Nyhan disease was studied during three learning paradigms: punishment, positive reinforcement and time out from reinforcement following an attempt at self injury. Punishment of self injury…
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