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Dublin Core
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Title
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Treatment of Symptoms in Children with Q3 Conditions Scoping Review Results
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<a href="http://doi.org/10.3109/09638288.2014.993436" target="_blank" rel="noreferrer noopener">http://doi.org/10.3109/09638288.2014.993436</a>
Dublin Core
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Title
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Rett syndrome: establishing a novel outcome measure for walking activity in an era of clinical trials for rare disorders
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Disability and Rehabilitation
Date
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2015
Subject
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Rehabilitation; validity; injury; Rett syndrome; walking; disease; sample; accelerometry; accuracy; activity monitors; Outcome measure; physical activity; physical-activity; step; test-retest reliability; tone and motor problems; tool development; scale development; StepWatch
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Downs J; Leonard H; Jacoby P; Brisco L; Baikie G; Hill K
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Background: Rett syndrome is a pervasive neurological disorder with impaired gait as one criterion. This study investigated the capacity of three accelerometer-type devices to measure walking activity in Rett syndrome. Methods: Twenty-six participants (mean 18 years, SD 8) wore an Actigraph, ActivPAL and StepWatch Activity Monitor (SAM) during a video-taped session of activities. Agreement was determined between step-counts derived from each accelerometer and observation. Repeatability of SAM-derived step counts was determined using pairs of one-minute epochs during which the same participant was observed to walk with the same cadence. Results: The mean difference (limit of agreement) for the Actigraph, ActivPAL and SAM were -41 (SD 33), -16 (SD 21) and -1 (SD 16) steps/min, respectively. Agreement was influenced by a device/cadence interaction (p < 0.001) with greater under-recording at higher cadences. For SAM data, repeatability of step-count pairs was excellent (intraclass correlation coefficient 0.91, 95% CI 0.79-0.96). The standard error of measurement was 6 steps/min and we would be 95% confident that a change >= 17 steps/min would be greater than within-subject measurement error. Conclusions: The capacity of the SAM to measure physical activity in Rett syndrome allows focus on participation-based activities in clinical practice and clinical trials.
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<a href="http://doi.org/10.3109/09638288.2014.993436" target="_blank" rel="noreferrer noopener">10.3109/09638288.2014.993436</a>
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
2015
accelerometry
accuracy
activity monitors
Baikie G
Brisco L
Disability And Rehabilitation
Disease
Downs J
Hill K
injury
Jacoby P
Leonard H
outcome measure
physical activity
physical-activity
Rehabilitation
Rett syndrome
sample
scale development
step
StepWatch
test-retest reliability
tone and motor problems
tool development
Validity
Walking