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Text
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Citation List Month
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URL Address
<a href="http://doi.org/10.1080/08880010500198285" target="_blank" rel="noreferrer">http://doi.org/10.1080/08880010500198285</a>
Dublin Core
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Title
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Osteoporosis at presentation of childhood ALL: management with pamidronate
Publisher
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Pediatric Hematology And Oncology
Date
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2005
Subject
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Child; Female; Humans; Male; Leukemia; Preschool; Clodronate; Acute; Lymphocytic; Bone Density/drug effects; Diphosphonates/administration & dosage; Fractures; Bone Density Conservation Agents/administration & dosage; L1/complications/radiography/therapy; Osteoporosis/drug therapy/etiology/radiography; Spinal Fractures/drug therapy/etiology/radiography; Spontaneous/drug therapy/etiology/radiography
Creator
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Goldbloom EB; Cummings EA; Yhap M
Description
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Vertebral fractures at diagnosis of childhood acute lymphoblastic leukemia (ALL) are an uncommon but recognized problem. Clinical issues associated with pathological fractures in these children include pain control and the potential for further treatment-associated fractures and long-term bony morbidity. The authors report the successful use of pamidronate in two children who presented with vertebral compression fractures at diagnosis of ALL. Both patients had pain and low bone mineral density at baseline. In addition to standard chemotherapy, pamidronate (1 mg/kg, IV) was given bimonthly. Initial rapid symptom relief and gradual improvement of bone mineral density was demonstrated in both patients.
2005
Identifier
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<a href="http://doi.org/10.1080/08880010500198285" target="_blank" rel="noreferrer">10.1080/08880010500198285</a>
Rights
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Article information provided for research and reference use only. PedPalASCNET does not hold any rights over the resource listed here. All rights are retained by the journal listed under publisher and/or the creator(s).
Type
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Journal Article
2005
Acute
Backlog
Bone Density Conservation Agents/administration & dosage
Bone Density/drug effects
Child
Clodronate
Cummings EA
Diphosphonates/administration & dosage
Female
Fractures
Goldbloom EB
Humans
Journal Article
L1/complications/radiography/therapy
Leukemia
Lymphocytic
Male
Osteoporosis/drug therapy/etiology/radiography
Pediatric Hematology And Oncology
Preschool
Spinal Fractures/drug therapy/etiology/radiography
Spontaneous/drug therapy/etiology/radiography
Yhap M